• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Eye Science >Fresh Amniotic Membrane Transplantation Combined Lamellar Keratoplasty for Patients with Recurrent Mooren's Ulcer
【24h】

Fresh Amniotic Membrane Transplantation Combined Lamellar Keratoplasty for Patients with Recurrent Mooren's Ulcer

机译：新鲜羊膜移植联合层状角膜移植术治疗复发性摩尔人溃疡

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Purpose: To investigate the possibility of amniotic membrane as an immunological insulating band to reduce the recurrent frequency of Mooren's ulcer. Methods: Twelve cases(12 eyes) with recurrent Mooren's Ulcer were observed. Among them, 4 cases(4 eyes) were male and 8 cases(8 eyes)female, ranging in age between 26 and 51 years [mean (41 +- 3) years]. Three eyes recurred once, 5 eyes twice, and 4 eyes three before. Eleven of 12 cases (11/12 eyes) with frequently recurrent Mooren's ulcer underwent lamellar keratoplasty combined amniotic membrane transplantation (AMT). One patient who had entire corneal ulceration accepted AMT alone. Results: Follow-up time is 12 to 29 months, [mean (23 +- 6) months]. Before AMT, the recurrent frequency of Mooren's Ulcer of all cases after corneal surgery was 1～7 months [mean(3 +- 2)months]. Nine of 12 eyes with lamellar keratoplasty combined AMT did not recur within the observation period; 2 eyes recurred 11 months after the surgery. Three months postoperatively, neovascularization was observed, which made it nearly impossible to decipher between amniotic membrane and its nearby conjunctiva, only at the junction of the transplant can some trails be observed. One case with entire AMT alone showed graft resolution and neovascularization in 1 month. Conclusion: AMT combined with lamellar keratoplasty and lesion excision may delay recurrence of Mooren's Ulcer, reduce its recurrent frequency. Besides the effects of decreasing inflammation, it may have immunological insulating function as well. This conclusion should be proven by further clinical comparative study of much more samples.
机译：目的：探讨羊膜作为免疫隔离带减少穆恩溃疡复发频率的可能性。方法：观察12例（12眼）复发性Mooren氏溃疡。其中男4例（4眼），女8例（8眼），年龄26〜51岁（平均（41±3）岁）。一次重复出现三只眼，两次重复出现五只眼，第三次出现四只眼。 12例（11/12眼）频繁复发的Mooren溃疡患者中，有11例接受了层板角膜移植联合羊膜移植（AMT）。一名患有整个角膜溃疡的患者仅接受AMT。结果：随访时间为12到29个月，[平均（23±6）个月]。在AMT之前，所有病例角膜手术后Mooren溃疡的复发频率为1〜7个月[平均（3 +-2）个月]。在观察期内12眼中有9眼未发生板状角膜移植联合AMT复发。术后11个月复发2只眼。术后三个月，观察到新血管形成，几乎不可能在羊膜及其附近的结膜之间解密，只有在移植物的交界处才能观察到一些痕迹。 1例仅使用AMT的患者在1个月内显示出移植物的分辨率和新血管形成。结论：AMT结合板层角膜移植和病灶切除可延迟Mooren溃疡的复发，降低其复发频率。除了减少炎症的影响外，它还可能具有免疫隔离功能。该结论应通过对更多样本进行进一步的临床比较研究来证明。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号