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Determination of phthalate esters in breast milk before and after frozen storage in milk storage bags

机译：在牛奶储存袋中冷冻储存前后乳头牛奶中邻苯二甲酸酯的测定

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摘要

This study describes the migration of 20 phthalates from breast milk storage bags to breast milk after storage frozen for 1 to 6 months. Analysis of the investigated phthalates was performed by GC-MS/MS. Nine phthalates were found in some of the 27 breast milk storage bags, six phthalates were detected in some of the 40 breast milk samples, but the concentrations were low, except for one sample, which contained dibutyl phthalate (DBP) at the level of 211.2 μg/kg. For most of the breast milk samples stored in breast milk storage bags, the migration of diisobutyl phthalate (DIBP), DBP and di-ethyl-hexyl phthalate (DEHP) increased with increasing storage time, but the migration of DBP and DEHP was lower than the migration limits of 300 μg/kg and 1500 μg/kg from the National Standards of the PRC even after storage for six months. The average daily intakes of DMP, DEP, DIBP, DBP and DEHP were 0.099,0.39, 0.62, 2.89 and 1.13 μg/kg/d, respectively, and the hazard indices were far below 1.
机译：本研究描述了在储存1至6个月后将20邻苯二甲酸盐从母乳储存袋中迁移到母乳中。通过GC-MS / MS进行研究的邻苯二甲酸盐的分析。在一些27个母乳储存袋中发现了九个邻苯二甲酸盐，在一些40个母乳样品中检测到六个邻苯二甲酸盐，但除了一个样品之外，浓度低，其在211.2的水平下含有邻苯二甲酸二丁酯（DBP）。 μg/ kg。对于储存在母乳储存袋中的大多数母乳样品，邻苯二甲酸二异丁酯（DIBP），DBP和邻苯二甲酸二乙酯（DEHP）的迁移随着储存时间的增加而增加，但DBP和DEHP的迁移低于即使在储存六个月后，PRC的国家标准也为300μg/ kg和1500μg/ kg的迁移限制。 DMP，DEP，DIBP，DBP和DOHP的平均每日摄入量分别为0.099,0.39,0.62,2.89和1.13μg/ kg / d，危险指数远低于1。

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  • 来源
    《Food additives & contaminants》 |2020年第11期|1897-1905|共9页
  • 作者

    Ji-Cai Fan; Ren Ren; Hua-Li He; Quan Jin; Shu-Ting Wang;

  • 作者单位

    Laboratory of Chemistry and Physics Hangzhou Center for Disease Control and Prevention Hangzhou P. R. China;

    Laboratory of Chemistry and Physics Hangzhou Center for Disease Control and Prevention Hangzhou P. R. China;

    Laboratory of Chemistry and Physics Hangzhou Center for Disease Control and Prevention Hangzhou P. R. China;

    Laboratory of Chemistry and Physics Hangzhou Center for Disease Control and Prevention Hangzhou P. R. China;

    Laboratory of Chemistry and Physics Hangzhou Center for Disease Control and Prevention Hangzhou P. R. China;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Migration; phthalate esters; breast milk; breast milk storage bag; GC-MS/MS; health risks;

    机译：移民;邻苯二甲酸酯;母乳;母乳储存袋;GC-MS / MS;健康风险;

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