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Evidence on correlation between number of disulfide bridge and toxicity of class IIa bacteriocins

机译:二硫桥数目与IIa类细菌素毒性之间相关性的证据

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The aim of this work was to study in the same microbiological conditions and for the first time the inhibitory action of eight class IIa bacteriocins against 23 Gram-positive bacteria in which some of them are industrially used as starters and against the eight class IIa bacteriocins producing strains themselves. The sensitivity of each strain was determined after MPA using the mathematical model described by Cabo et al. (1999, J. Appl. Microbiol. 87, 907-914). Therefore, the principal component analysis realized led to a strong correlation between spectrum and extra-disulfide bridge and a minor correlation between spectrum and isoelectric point of each bacteriocin.
机译:这项工作的目的是在相同的微生物条件下进行研究,这是首次研究八种IIa类细菌素对23种革兰氏阳性细菌的抑制作用,其中某些革兰氏阳性细菌在工业上用作发酵剂,并且对八种IIa类细菌素产生抑制作用。劳累自己。在MPA之后,使用Cabo等人描述的数学模型确定每种菌株的敏感性。 (1999,J.Appl.Microbiol.87,907-914)。因此,实现的主成分分析导致光谱与二硫键之间的强相关性,以及每种细菌素的光谱与等电点之间的相关性较小。

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