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Chemical profiles and hypoglycemic activities of mulberry leaf extracts vary with ethanol concentration

机译:桑叶提取物的化学特征和降血糖活性随乙醇浓度而变化

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摘要

Five mulberry leaf extracts (water, 25, 50, 75, and 100% EtOH) were characterized for in vitro hypoglycemic activity and chemical profiles. According to chemical profiles obtained from 15Tesla Fourier transform ion cyclotron resonance mass spectrometry, water extracts contained more 1-deoxynojirimycin (DNJ) and fewer phytochemicals than other extracts. However, water extracts showed the highest inhibitory activity of glucose uptake. The degree of inhibition of α-glucosidase activity was similar for all extracts. The effect of mulberry leaf extracts on the glucose metabolism may be attributed to additional or cooperative effects of DNJ with other phytochemical compounds.
机译:表征了五种桑叶提取物(水,25%,50%,75%和100%EtOH)的体外降血糖活性和化学特性。根据从15Tesla傅里叶变换离子回旋共振质谱法获得的化学概况,与其他提取物相比,水提取物含有更多的1-脱氧野oji霉素(DNJ)和更少的植物化学物质。但是,水提取物显示出最高的葡萄糖摄取抑制活性。所有提取物的α-葡萄糖苷酶活性抑制程度均相似。桑叶提取物对葡萄糖代谢的影响可能归因于DNJ与其他植物化学化合物的附加或协同作用。

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