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Hypocholesterimic effects of cold and hot extracted virgin coconut oil (VCO) in comparison to commercial coconut oil: Evidence from a male wistar albino rat model

机译:冷和热提取的初榨椰子油(VCO)与市售椰子油相比的降胆固醇作用:来自雄性wistar白化病大鼠模型的证据

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摘要

The hypolipidemic effect of cold extracted virgin coconut oil (CEVCO) and hot extracted virgin coconut oil (HEVCO) compared to commercially available coconut oil (CCO) was studied using male wistar rats. Groups were designated as control, hypercholesterimic control (HC Control), HC+10% (CEVCO), HC+15% (CEVCO), HC+10% (HEVCO), HC+15% (HEVCO) and HC+15% (CCO). Control rats were fed a basal diet while other groups were initially fed a hypercholesterimic diet (2% cholesterol and 0.25% bile salts) for 15 days, then fed with CEVCO or HEVCO (both at 10% and 15% levels), and commercial coconut oil (15%) for 30 days. Total cholesterol and LDL cholesterol levels were significantly (p<0.05) decreased by approximately 25 and 40%, respectively, in the blood plasma, while HDL cholesterol increased significantly (p<0.05) by approximately 21% in HEVCO fed rats. Tissue cholesterol and triacylycerol (TAG) levels in both liver and heart tissues decreased significantly (p<0.05) in CEVCO and HEVCO fed animals, compared with CCO fed rats.
机译:使用雄性Wistar大鼠研究了冷提取的初榨椰子油(CEVCO)和热提取的初榨椰子油(HEVCO)与市售椰子油(CCO)相比的降血脂作用。将组指定为对照组,高胆固醇血症对照组(HC对照),HC + 10%(CEVCO),HC + 15%(CEVCO),HC + 10%(HEVCO),HC + 15%(HEVCO)和HC + 15%( CCO)。对照组大鼠接受基础饮食喂养,而其他组最初接受高胆固醇饮食(2%胆固醇和0.25%胆汁盐)持续15天,然后喂养CEVCO或HEVCO(水平分别为10%和15%)和商业椰子油(15%)30天。在HEVCO喂养的大鼠中,血浆中的总胆固醇和LDL胆固醇水平分别显着降低(p <0.05)25%和40%,而HDL胆固醇显着提高(p <0.05)大约21%。与CCO喂养的大鼠相比,CEVCO和HEVCO喂养的动物肝脏和心脏组织的组织胆固醇和三酰甘油(TAG)水平显着降低(p <0.05)。

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