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Antioxidant, anti-inflammatory activity, and phytochemical constituents of ficus (Ficus amplissima Smith) bark

机译:榕树皮(Ficus amplissima Smith)的抗氧化,抗炎活性和植物化学成分

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摘要

In the present investigation, phenolics (36.6 g gallic acid equivalents (GAE)/100 g extract), tannin (21.6 g GAE/100 g extract), and flavonoid content (67.5 g rutin equivalents/100 g extract) were found to be highest in acetone extract. Ficus (Ficus amplissima) acetone extract showed maximum antioxidant activity in phosphomolybdenum (958.8 mg ascorbic acid equivalents/g extract), DPPH (1.6 μg/mL), ferric reducing antioxidant power (2,993 mmol Fe (II)/g extract), and metal chelating (39.7 mg EDTA equivalents/g extract) assays. In anti-inflammatory study, 400 mg/kg acetone extract showed maximum reduction in the paw volume compare to indomethacin. GC-MS analysis indicated that bark contain rich source of non-polar compounds like Lup-20(29)-en-3-yl acetate (33.04%). Hence, Ficus can be valuable source for antioxidant and anti-inflammatory and seemed to be applicable in medicine.
机译:在本研究中,发现酚类化合物(36.6 g没食子酸当量(GAE)/ 100 g提取物),单宁(21.6 g GAE / 100克提取物)和类黄酮含量(67.5 g芦丁当量/ 100 g提取物)最高。在丙酮提取物中。榕(Ficus amplissima)丙酮提取物在磷钼(958.8 mg抗坏血酸当量/ g提取物),DPPH(1.6μg/ mL),三价铁还原抗氧化剂能力(2,993 mmol Fe(II)/ g提取物)和金属中显示出最大的抗氧化活性螯合(39.7毫克EDTA当量/克提取物)测定。在抗炎研究中,与消炎痛相比,400 mg / kg丙酮提取物显示出最大的爪缩量。 GC-MS分析表明,树皮含有丰富的非极性化合物,如Lup-20(29)-en-3-yl乙酸酯(33.04%)。因此,榕树可能是抗氧化剂和抗炎药的宝贵来源,似乎可用于医学领域。

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