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首页> 外文期刊>Food Science and Biotechnology >Oral administration of fingerroot (Boesenbergia pandurata) extract reduces ultraviolet b-induced skin aging in hairless mice
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Oral administration of fingerroot (Boesenbergia pandurata) extract reduces ultraviolet b-induced skin aging in hairless mice

机译：口服指根提取物（Boesenbergia pandurata）可减少紫外线b引起的无毛小鼠皮肤衰老

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摘要

Fingerroot [Boesenbergia pandurata (Roxb.) Schltr.], belonging to Zingiberaceae, is an edible tropical medicinal plant that has been traditionally used to treat various diseases. However, the effect of its oral intake on skin has not yet been reported. This study aimed to investigate anti-photoaging effects of the ethanol extract of fingerroot in a hairless mouse model. Compared with the untreated UVB control group, mice that received fingerroot extract (BPE) showed significantly reduced wrinkle formation, skin thickening, and transepidermal water loss in dorsal skin irradiated with UVB. Moreover, BPE significantly prevented UVB-induced matrix metalloproteinase (MMP)-3 and -13 expressions and also MMP-2 and -9 activities. These results strongly suggest that oral administration of BPE confers in vivo anti-photoaging effects in hairless mice. Thus, fingerroot may have potential as an oral photoprotective agent to prevent skin photoaging following UV exposure.
机译：Fingerroot [Boesenbergia pandurata（Roxb。）Schltr。]，属于姜科，是一种可食用的热带药用植物，传统上用于治疗各种疾病。然而，尚未报道其口服摄入对皮肤的影响。这项研究旨在研究无毛小鼠模型中指根乙醇提取物的抗光老化作用。与未经治疗的UVB对照组相比，接受指根提取物（BPE）的小鼠在用UVB照射的背部皮肤中，皱纹形成，皮肤增厚和经表皮水分流失明显减少。此外，BPE显着阻止了UVB诱导的基质金属蛋白酶（MMP）-3和-13的表达以及MMP-2和-9的活性。这些结果强烈提示口服BPE可在无毛小鼠体内产生抗光老化作用。因此，指根可能具有作为口服光保护剂的潜力，可以防止紫外线照射后皮肤光老化。

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