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首页> 外文期刊>Food science and technology research >Simultaneous Effects of Green Tea Extracts and Fish Oil on Mercury Accumulation and Antioxidant Defenses in Methylmercury-exposed Adult Mice
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Simultaneous Effects of Green Tea Extracts and Fish Oil on Mercury Accumulation and Antioxidant Defenses in Methylmercury-exposed Adult Mice

机译：绿茶提取物和鱼油对甲基汞暴露成年小鼠体内汞累积和抗氧化防御的同时影响

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摘要

Male mice (4 months old) were fed green tea extract- (GTE; 0.25% w/w) and/or fish oil- (FO; 5% w/w) containing diets with 8 ppm methylmercury (MeHg) chloride for 4 months to investigate the effects of simultaneous intakes on brain functions, antioxidant defenses against MeHg, and MeHg accumulation in tissues. In mouse maze tests, intake of GTE or FO significantly improved the learning ability of MeHg-ex-posed mice. GTE and FO also significantly decreased liver and brain catalase activities in MeHg-exposed mice. Total Hg concentrations in muscle were significantly lowered by dietary GTE and FO in the MeHg-exposed group, though no remarkable differences were observed in the brain. These data indicate that simultaneous intake of GTE and FO effectively prevents MeHg-mediated oxidative stress and reduces the effects of Hg exposure with fish consumption.
机译：给雄性小鼠（4个月大）喂食含有8 ppm甲基汞（MeHg）氯化物饮食的绿茶提取物（GTE; 0.25％w / w）和/或鱼油-（FO; 5％w / w）4个月研究同时摄入对脑功能，抗MeHg的抗氧化防御以及MeHg在组织中积累的影响。在小鼠迷宫测试中，摄入GTE或FO可以显着提高暴露于MeHg的小鼠的学习能力。 GTE和FO还显着降低了暴露于MeHg的小鼠的肝脏和大脑过氧化氢酶活性。饮食中的GTE和FO在暴露于MeHg的组中的肌肉中总Hg浓度显着降低，尽管在大脑中未观察到显着差异。这些数据表明，同时摄入GTE和FO可有效防止MeHg介导的氧化应激，并减少食用鱼类对Hg暴露的影响。

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  • 来源
    《Food science and technology research》 |2013年第5期|883-891|共9页
  • 作者

    Nobuya Shirai; Yumiko Yamashita; Michiaki Yamashita;

  • 作者单位

    National Agriculture and Food Research Organization, National Food Research Institute, 2-1-12, Kannondai, Tsukuba, Ibaraki 305-8642, Japan,National Agriculture and Food Research Organization, National Institute of Vegetable and Tea Science, 2769 Kanaya, Shimada, Shizuoka 428-8501 Japan;

    National Research Institute of Fisheries Science, Fisheries Research Agency, 2-12-4 Fukuura, Kanazawa, Yokohama, Kanagawa 236-8648, Japan;

    National Research Institute of Fisheries Science, Fisheries Research Agency, 2-12-4 Fukuura, Kanazawa, Yokohama, Kanagawa 236-8648, Japan;

  • 收录信息 美国《科学引文索引》(SCI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    fish oil; green tea; methylmercury; ascorbic acid; thiobarbituric acid reactive substances;

    机译：鱼油;绿茶;甲基汞抗坏血酸;硫代巴比妥酸反应性物质;

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