Gene Machine

Matthew Herper

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Gene Machine

机译：基因机

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摘要

On the ground floor of an office build-ing in a rundown neighborhood in Menlo Park, Calif., two lasers fire inside a dresser-size aluminum alloy cabinet. The beams bounce off mirrors and through lenses toward a foot-high, six-legged contraption that looks like a robot insect. There they converge in the center of a glass slide the size of a fingernail on a point the diameter of the head of a pin.rnThat point is full of thousands and thousands of tiny holes, each smaller than the smallest transistor. Roughly a third of the holes contain tiny loops of DNA circling through a mutated enzyme in a soup of molecules tagged with luminescent dyes. Each letter of genetic code creates a tiny flash of a dif ferent color of light, which is picked up by a camera and read into a computer.

机译：在加州门洛帕克（Menlo Park）一座破败不堪的社区的一栋办公楼的底楼，一台梳妆台大小的铝合金柜子内发射了两束激光。光束从镜子反射，并通过透镜射向看上去像机器人昆虫的六英尺高的脚装置。它们会聚在玻璃滑动片中心，其大小相当于指甲的直径在一个针头直径的点上。该点充满了成千上万个小孔，每个小孔都比最小的晶体管小。大约三分之一的孔中有微小的DNA环，这些环围绕着用荧光染料标记的分子汤中的突变酶盘旋。遗传密码的每个字母都会产生不同颜色的微小闪光，然后由照相机将其拾取并读入计算机。

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《Forbes》 |2009年第6期|6062-63|共3页
作者
Matthew Herper;
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收录信息美国《科学引文索引》(SCI);
原文格式 PDF
正文语种 eng
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Gene Machine

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