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首页> 外文期刊>Deutsche Zeitschrift fur Sportmedisin >Der Einfluß eines moderaten Ausdauertrainings auf die Leptinkonzentration im Serum
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Der Einfluß eines moderaten Ausdauertrainings auf die Leptinkonzentration im Serum

机译：中等耐力训练对血清瘦素浓度的影响

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摘要

The purpose of the present investigation was to assess the influence of physical activity on serum leptin levels. 25 leisure time athletes participated in a 3-months training program. Subjects exercised three to four days per week for 45 minutes/day and a maximal training volume of 30 km/week. The intensity of exercise was determined by lactic acid levels, the subjects exercised between 2-3 mmol/l lactic acid. The aerobic capacity (4 mmol lactic acid threshold) increased significantly from 3,08 ± 0,64 to 3,33 ± 0,61 m/s (p=0,000) after the training period. Serum leptin levels rose significantly from 4,95 ± 4,7 to 6,33 ± 6,18 ng/ml (p=0,004), whereas the Body Mass Index remained unchanged. Serum leptin was measured by RIA (Fa. Me-diagnost Tubingen). The increased energy turnover at a well adjusted energy balance seems to elevate serum leptin. 13 leisure time athletes completed an acute bout of exercise with a 2,5 hours extensive run. Serum leptin, creatinine and free fatty acids were determined before, immediately after the run, and-during the recovery period, 1h, 2h, 6h and 24h after the run. Serum leptin decreased significantly from 1,36 ± 1,06 to 0,93 ± 0,74 ng/ml (p=0,002) and 24h after the run the leptin levels were still significantly lower (1,05 ± 1,14 ng/ml) than the pre-race values. The decreased serum leptin after strenuous exercise are in agreement with previous basic research studies, for the leptin production in the adipocyte is suppressed by catechola-mines and free fatty acids, as they can be observed under this kind of exercise. Leptin, the ,,sensor of energy balance" seems to be closely related to energy metabolism and is influenced by volume and intensity of training.
机译：本研究的目的是评估体育锻炼对血清瘦素水平的影响。 25名业余时间运动员参加了为期3个月的培训计划。受试者每周运动三到四天，每天运动45分钟，最大运动量为每周30公里。运动强度由乳酸水平决定，受试者在2-3 mmol / l乳酸之间运动。训练期后，有氧能力（乳酸阈值为4 mmol）从3,08±0,64显着增加至3,33±0,61 m / s（p = 0,000）。血清瘦素水平从4,95±4,7 ng显着上升至6,33±6,18 ng / ml（p = 0,004），而体重指数保持不变。血清瘦素通过RIA（Fa.Me-diagnost Tubingen）测量。在良好调节的能量平衡下增加的能量转换似乎可以提高血清瘦素。 13名业余时间运动员经过2.5小时的长时间跑步，完成了剧烈的运动。在运行前，运行后以及运行后1h，2h，6h和24h期间测定血清瘦素，肌酐和游离脂肪酸。血清瘦素从1,36±1,06 ng显着降低至0.93±0.74 ng / ml（p = 0,002），运行后24小时，瘦素水平仍显着降低（1,05±1,14 ng / ml）。 ml），而不是赛前值。剧烈运动后血清瘦素的降低与以前的基础研究一致，因为脂肪细胞中瘦素的生成被ca藤矿物质和游离脂肪酸抑制，正如在这种运动下可以观察到的那样。瘦素，“能量平衡的传感器”似乎与能量代谢密切相关，并受训练量和强度的影响。

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