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Robot-assisted radical hysterectomy—perioperative and survival outcomes in patients with cervical cancer compared to laparoscopic and open radical surgery

机译:机器人辅助根治性子宫切除术-与腹腔镜和开放性根治性手术相比,宫颈癌患者的围手术期和生存结果

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In this study, perioperative outcomes and survival data in patients with early cervical cancer operated with three surgical methods: robot-assisted, laparoscopic and open, are to be analyzed. From January 2006 to May 2010, 294 patients with T1в1 cervical cancer were studied retrospectively. Robot-assisted radical hysterectomy (RARH) was performed in 73 (24.8%) of them, laparoscopic-assisted radical vaginal hysterectomy (LARVH) in 46 (15.6%) and, in 175, (59.5%), abdominal radical hysterectomy (ARH). Mean hospital stay of patients with RARH and LARVH was 4.1 ± 0.7 and 4.8 ± 0.5, respectively, and of those with ARH, 9.6 ± 1.0 days (p = 0.001). Mean operative time was 152.2 ± 26.5 min for the robotic group as it was significantly shorter in comparison with the laparoscopic group (232.1 ± 61.7 min) and laparotomy group (168.2 ± 31.1 min) (p = 0.001). The application of Cox regression analysis found that the regional lymph node metastases were of significant value for disease-free survival (DSF), and the nodal status and recurrence presence—for overall survival (OS). Type of surgical procedure did not influence DSF, as well as OS. RARH has been established to be a safe procedure with proven advantages in regard to operative time and hospital stay. The absence of significant differences in DSF and OS is a substantial reason to continue, from an oncologic point of view, the application of this method on patients with T1в1 cervical cancer.
机译:在这项研究中,将对采用三种手术方法(机器人辅助,腹腔镜和开放式手术)的早期宫颈癌患者的围手术期结果和生存数据进行分析。 2006年1月至2010年5月,对294例T1?1宫颈癌患者进行了回顾性研究。其中73例(24.8%)进行了机器人辅助的根治性子宫切除术(RARH),其中46例(15.6%)进行了腹腔镜辅助的根治性阴道子宫切除术(LARVH),175例(59.5%)进行了腹部根治性子宫切除术(ARH) 。 RARH和LARVH患者的平均住院时间分别为4.1±0.7和4.8±0.5,而ARH患者的平均住院时间为9.6±1.0天(p = 0.001)。机器人组的平均手术时间为152.2±26.5 min,因为与腹腔镜手术组(232.1±61.7 min)和剖腹手术组(168.2±31.1 min)相比,手术时间明显缩短了(p = 0.001)。 Cox回归分析的应用发现,区域淋巴结转移对于无病生存期(DSF)以及淋巴结状态和复发存在-总体生存期(OS)具有重要价值。手术程序的类型不影响DSF以及OS。 RARH已被确立为一种安全的程序,在手术时间和住院时间方面具有公认的优势。从肿瘤学的角度来看,DSF和OS没有明显差异是继续将该方法应用于T1?1宫颈癌患者的重要原因。

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