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首页> 外文期刊>Head and Neck Pathology >Pseudotumor of the Mandible as First Presentation of Hemophilia in a 2-Year-Old Male: A Case Report and Review of Jaw Pseudotumors of Hemophilia
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Pseudotumor of the Mandible as First Presentation of Hemophilia in a 2-Year-Old Male: A Case Report and Review of Jaw Pseudotumors of Hemophilia

机译：下颌骨假性血友病在2岁男性中的首次表现：一例报道和下颌血友病假性假瘤回顾

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摘要

Pseudotumor of hemophilia (PTH) is a rare complication seen in approximately 1–2% of cases of hemophilia. Although much more common in long bones, the pelvis, and small bones of the hands and feet than in the jaws, occasionally hemorrhage in the jaws occurs with this result. We present a case in a two-year-old male with a one-month swelling of the right mandible without significant medical history or diagnosis of hemophilia who was subsequently diagnosed as having Factor IX deficiency, or hemophilia B. A review of the literature revealed only 15 reported cases of PTH of the jaws and salient features of PTH in the jaws are discussed. The differential diagnosis of masses occurring in the jaws of children is limited and PTH should be considered when a mass presents with rapid growth and the histopathologic features are not diagnostic for a neoplastic process, even in the absence of a prior diagnosis of hemophilia as PTH may be the initial manifestation of this disease.
机译：血友病的假瘤（PTH）是一种罕见的并发症，约占血友病病例的1-2％。尽管在长骨，骨盆以及手和脚的小骨头中比在下颚中更常见，但有时在下颚中会出现出血。我们介绍了一例两岁男性，右下颌骨肿胀一个月，没有明显的病史或血友病诊断，后来被诊断为IX因子缺乏症或血友病B。文献回顾仅讨论了15例报告的颌骨PTH病例和颌骨PTH的显着特征。在儿童颌骨中发生的肿块的鉴别诊断是有限的，当肿块呈快速增长并且组织病理学特征不能诊断为赘生性肿瘤时，应考虑考虑PTH，即使没有事先诊断为血友病，因为PTH可能是这种疾病的最初表现。

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