...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Human physiology >Analysis of Possible Causes of Activation of Gastric and the Pancreatic Excretory and Incretory Function after Completion of Space Flight at the International Space Station
【24h】

Analysis of Possible Causes of Activation of Gastric and the Pancreatic Excretory and Incretory Function after Completion of Space Flight at the International Space Station

机译：国际空间站完成空间飞行后，胃激活及胰腺排泄和排泄功能激活的可能原因分析

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A comparative analysis of the excretory and incretory activity of the stomach and pancreas in astronauts soon after completion of space flights of various durations was performed. An increase in the fasting activity of gastric and pancreatic enzymes and hormones (insulin and C-peptide) in blood, reflecting the increased excretory and incretory activity of organs of the gastroduodenal region developing in microgravity, was demonstrated. The absence of subjects infected with Helicobacter pylori in the space flight crew excluded the involvement of this microorganism in the mechanism underlying the increase in the gastric secretory activity. The absence of correlation between the increase in the secretory activity of organs of the gastroduodenal region and the duration of the space flight allowed us to rule out the hypokinetic mechanism, which is associated with the duration of exposure to microgravity. It was concluded that the main mechanism underlying the changes in the functional state of the digestive system in space flight may be determined by the rearrangement of the venous hemodynamics of organs of the abdominal cavity, unrelated to the duration of exposure to microgravity. It was shown that, after completion of space flights and in ground-based experiments simulating the hemodynamic rearrangement occurring in microgravity, the increase in the basal excretory activity of gastroduodenal organs was not caused by gastrin secretion and occurred simultaneously with an increase in the secretion of insulin, which is considered as a putative hormonal component of the hemodynamic mechanism.
机译：在完成各种持续时间的太空飞行后不久，对宇航员的胃和胰腺的排泄和排泄活动进行了比较分析。结果表明，血液中胃和胰酶和激素（胰岛素和C肽）的禁食活性增加，反映了在微重力下发展的胃十二指肠区域器官的排泄和排泄活性增加。航天飞机上没有幽门螺杆菌感染的受试者，排除了这种微生物参与胃分泌活性增加的机制。胃十二指肠区域器官分泌活动的增加与航天飞行的持续时间之间不存在相关性，这使我们可以排除动力不足的机制，这与暴露于微重力的持续时间有关。结论是，太空飞行中消化系统功能状态变化的主要机制可能是由腹腔器官静脉血流动力学的重排决定的，而与重重力暴露的持续时间无关。结果表明，完成航天飞行并在模拟微重力下发生的血液动力学重排的地面实验中，胃十二指肠器官的基础排泄活性增加不是由胃泌素分泌引起的，而是与胃泌素分泌增加同时发生的。胰岛素，被认为是血液动力学机制的一种激素成分。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号