• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>IEE Proceedings. Part M, Nanobiotechnology >Silica microspheres for biomolecular detection applications
【24h】

Silica microspheres for biomolecular detection applications

机译：用于生物分子检测的二氧化硅微球

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Microsphere-based biosensors have been attracting the attention of the photonics community due to their high sensitivity, selectivity and implementation. Microspheres, with their high quality-factor (Q-factor) morphology dependent resonances, are very sensitive to refractive index and size changes. The perturbation of the microsphere morphology dependent resonances can be used for the detection of biomolecules. Adsorption of different biomolecules on the surface of microspheres causes a change of effective size and refractive index leading to the shift of resonance wavelengths. A biosensor, based on this phenomenon, can detect a single molecule sensitively depending on the configuration that needs to be designed and optimised. Silica with a refractive index of 1.5, which is very close to that of bimolecular agents, is a suitable photonic material to use for biosensing applications. The transverse electric and transverse magnetic elastic scattering spectra at 90° and 0° are calculated at 1.55 μm with the associated shifts after adding a layer on it. 90° scattering is used to monitor the scattered signal, whereas 0° scattering is used to monitor the transmission signal.
机译：基于微球的生物传感器由于其高灵敏度，选择性和可实现性而吸引了光子学界的关注。具有高质量因子（Q因子）形态相关共振的微球对折射率和尺寸变化非常敏感。微球形态依赖性共振的扰动可用于检测生物分子。微球表面上不同生物分子的吸附会导致有效尺寸和折射率的变化，从而导致共振波长的变化。基于此现象的生物传感器可以根据需要设计和优化的配置灵敏地检测单个分子。折射率为1.5的二氧化硅非常接近双分子试剂，是一种适用于生物传感应用的光子材料。在其上添加一层之后，在1.55μm处计算90°和0°时的横向电和横向磁弹性散射光谱。 90°散射用于监视散射信号，而0°散射用于监视传输信号。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号