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A Biochemical Translinear Principle With Weak Inversion ISFETs

机译:具有弱反转ISFET的生化跨线性原理

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A weak inversion region is shown to exist in ion-sensitive field effect transistor (ISFET) sensors. It is therefore proposed that the ISFET and its chemically sensitive (ChemFET) counterparts be used as translinear elements in the synthesis of novel biochemical input stages which perform real-time mathematical manipulation of biochemical signals. A Biochemical Translinear Principle using weakly inverted ChemFETs is presented. A low-power current-mode input stage circuit is presented as an application of the principle. This yields a linear relation between drain current and hydrogen ion concentration valid over four decades. This paper demonstrates an important and necessary step toward biochemical VLSI.
机译:离子敏感型场效应晶体管(ISFET)传感器中存在一个弱反转区。因此,建议在合成生物化学输入阶段的合成中,将ISFET及其化学敏感性(ChemFET)对应物用作超线性元素,这些输入阶段执行生物化学信号的实时数学处理。提出了使用弱反向ChemFET的生化跨线性原理。作为该原理的应用,提出了一种低功耗电流模式输入级电路。这产生了在四十年内有效的漏极电流和氢离子浓度之间的线性关系。本文展示了朝生化超大规模集成电路迈出的重要而必要的一步。

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