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首页> 外文期刊>Magnetics, IEEE Transactions on >Modified Solenoid Coil That Efficiently Produces High Amplitude AC Magnetic Fields With Enhanced Uniformity for Biomedical Applications
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Modified Solenoid Coil That Efficiently Produces High Amplitude AC Magnetic Fields With Enhanced Uniformity for Biomedical Applications

机译:改进的电磁线圈,可高效产生具有增强均匀性的高振幅交流磁场,用于生物医学应用

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摘要

In this paper, we describe a modified solenoid coil that efficiently generates high amplitude alternating magnetic fields (AMF) having field uniformity (≤10%) within a 125-cm3 volume of interest. Two-dimensional finite element analysis (2D-FEA) was used to design a coil generating a targeted peak AMF amplitude along the coil axis of ~ 100 kA/m (peak-to-peak) at a frequency of 150 kHz while maintaining field uniformity to >; 90% of peak for a specified volume. This field uniformity was realized by forming the turns from cylindrical sections of copper plate and by adding flux concentrating rings to both ends of the coil. Following construction, the field profile along the axes of the coil was measured. An axial peak field value of 95.8 ± 0.4 kA/m was measured with 650 V applied to the coil and was consistent with the calculated results. The region of axial field uniformity, defined as the distance over which field ≥ 90% of peak, was also consistent with the simulated results. We describe the utility of such a device for calorimetric measurement of nanoparticle heating for cancer therapy and for magnetic fluid hyperthermia in small animal models of human cancer.
机译:在本文中,我们描述了一种改进的螺线管线圈,该线圈可以在感兴趣的125 cm 3 范围内有效地产生具有磁场均匀性(≤10%)的高振幅交流磁场(AMF)。二维有限元分析(2D-FEA)用于设计一个线圈,该线圈在150 kHz的频率下沿〜100 kA / m(峰-峰)的线圈轴产生目标峰值AMF振幅,同时保持场均匀性到>;指定体积的峰的90%。通过从铜板的圆柱形部分形成匝并在线圈的两端添加磁通集中环来实现这种磁场均匀性。在构造之后,测量沿线圈轴线的磁场轮廓。在650 V的线圈上测得的轴向峰值磁场值为95.8±0.4 kA / m,与计算结果一致。轴向场均匀性区域(定义为场强≥峰值的90%的距离)也与模拟结果一致。我们描述了用于癌症治疗和用于人类癌症的小动物模型中的磁流体热疗的纳米量热的量热测量的这种装置的实用性。

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