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首页> 外文期刊>Ultrasonics, Ferroelectrics and Frequency Control, IEEE Transactions on >MR-guided adaptive focusing of ultrasound
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MR-guided adaptive focusing of ultrasound

机译：MR引导的超声自适应聚焦

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摘要

Adaptive focusing of ultrasonic waves under the guidance of a magnetic resonance (MR) system is demonstrated for medical applications. This technique is based on the maximization of the ultrasonic wave intensity at one targeted point in space. The wave intensity is indirectly estimated from the local tissue displacement induced at the chosen focus by the acoustic radiation force of ultrasonic beams. Coded ultrasonic waves are transmitted by an ultrasonic array and an MRI scanner is used to measure the resulting local displacements through a motion-sensitive MR sequence. After the transmission of a set of spatially encoded ultrasonic waves, a non-iterative inversion process is employed to accurately estimate the spatial-temporal aberration induced by the propagation medium and to maximize the acoustical intensity at the target. Both programmable and physical aberrating layers introducing strong distortions (up to 2<0; radians) were recovered within acceptable errors (<0.8 rad). This noninvasive technique is shown to accurately correct phase aberrations in a phantom gel with negligible heat deposition and limited acquisition time. These refocusing performances demonstrate a major potential in the field of MR-guided ultrasound therapy in particular for transcranial brain high-intensity focused ultrasound.
机译：演示了在磁共振（MR）系统的指导下对超声波的自适应聚焦技术，该技术在医疗领域的应用。该技术基于最大化空间中一个目标点处的超声波强度。根据超声波束的声辐射力在选定的焦点处引起的局部组织位移间接估算出波强度。编码的超声波由超声波阵列传输，并且MRI扫描仪用于通过运动敏感的MR序列测量所得的局部位移。在传输一组空间编码的超声波之后，采用非迭代反演过程来准确估计传播介质引起的时空像差并使目标处的声强最大化。在可接受的误差（<0.8 rad）内，恢复了引入强烈畸变（高达2 <0;弧度）的可编程和物理像差层。这项非侵入性技术显示可以精确地校正幻像凝胶中的相差，并且热量沉积可以忽略不计，并且采集时间有限。这些重新聚焦性能证明了在MR引导的超声治疗领域中的巨大潜力，特别是对于经颅脑高强度聚焦超声。

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