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The combined concentric-ring and sector-vortex phased array for MRI guided ultrasound surgery

机译:同心环和扇形涡流相控阵相结合的MRI指导的超声手术

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MRI guided ultrasound surgery requires small surgical equipment volumes to facilitate the treatment of larger patients in the limited space of a conventional MRI magnet. In addition, large focal volumes are required to reduce the treatment time of large tumors. The concentric-ring array is capable of moving the focus in one dimension, and previous studies have shown that a circular array composed of radial sectors is capable of producing enlarged focal volumes. These two array designs may be combined to create an array that is capable of both enlarging the focus and moving the focus along the axis of the array. Simulations were performed to predict the performance and capabilities of various combined array designs by using numerical routines to, calculate the acoustic power field, temperature distribution, and accumulated thermal dose. The results shown predict that the combined array can create necrosed tissue volumes over 30 times larger than the concentric-ring array while maintaining focal range. The simulation results were verified with an experimental array consisting of 13 rings and 4 sectors. In addition, simulations were performed where multiple focal patterns were cycled in the time domain to create an optimized heating pattern characterized by uniform thermal dose over the volume of the lesion. Such heating patterns resulted in a 40/spl deg/C lower maximum temperature compared to single mode sonications while producing the same necrosed tissue volume, and yielded a rate of necrosis of 26.4 cm/sup 3//h.
机译:MRI引导的超声手术需要较小的手术设备体积,以利于常规MRI磁体在有限空间内治疗较大的患者。另外,需要大的聚焦体积以减少大肿瘤的治疗时间。同心环阵列能够在一个维度上移动焦点,并且先前的研究表明,由径向扇形组成的圆形阵列能够产生更大的焦距。可以将这两个阵列设计组合以创建能够扩大焦点并沿着阵列的轴移动焦点的阵列。通过使用数值例程来计算声功率场,温度分布和累积的热剂量,进行了仿真以预测各种组合阵列设计的性能和功能。显示的结果表明,组合阵列可以产生坏死的组织体积,其体积是同心环阵列的30倍以上,同时又能保持聚焦范围。仿真结果通过由13个环和4个扇区组成的实验阵列进行了验证。另外,进行了模拟,其中在时域中循环多个聚焦模式以创建优化的加热模式,其特征在于病变体积上均匀的热剂量。与单模超声处理相比,这种加热方式导致最高温度降低40 / spl℃/℃,同时产生相同的坏死组织体积,并且产生26.4 cm / sup 3 // h的坏死率。

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