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首页> 外文期刊>International journal of food science & technology >Bioactive peptides from collagen hydrolysates from squid (Dosidicus gigas) by-products fractionated by ultrafiltration
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Bioactive peptides from collagen hydrolysates from squid (Dosidicus gigas) by-products fractionated by ultrafiltration

机译：乌贼副产物胶原水解产物的生物活性肽经超滤分离

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摘要

The bioactive properties of peptide fractions obtained from the hydrolysis of squid (Dosidicus gigas) by-products collagen, using Protease type XIV and ultrafiltration (UFI), were studied. The basic objective was to improve the bioactivity of squid hydrolysates via the application of UFI. Peptide fractions obtained after UFI had higher antioxidant and antimutagenic activities, but the antiproliferative activity did not improve after UFI. Peptides kDa (Fraction F3) showed higher antioxidant and antimutagenic activities, as well as lower antioxidant and antiproliferative activities than both, peptides 10 kDa (F1) and those within the range of 5 to kDa (F2). Band at lower field observed in FT-IR spectra and proton-peaks observed at higher H-1-NMR fields, both associated to aromatic amino acids, as well as to other antioxidant amino acids such as hydroxyproline, glycine, arginine and lysine, may explain F3 bioactivity. Ultrafiltration can, therefore, be used to improve some bioactivities of squid collagen hydrolysates.
机译：研究了使用XIV蛋白酶和超滤（UFI）水解鱿鱼（Dosidicus gigas）副产物胶原蛋白获得的肽级分的生物活性。基本目标是通过使用UFI来改善鱿鱼水解物的生物活性。 UFI后获得的肽级分具有较高的抗氧化和抗诱变活性，但UFI后其抗增殖活性并未提高。 kDa肽（F3级组分）比> 10 kDa肽（F1）和> 5到kDa范围内的肽（F2）都具有更高的抗氧化和抗诱变活性，以及​​较低的抗氧化和抗增殖活性。在FT-IR光谱中观察到的较低谱带和在较高H-1NMR场中观察到的质子峰可能与芳族氨基酸以及其他抗氧化剂氨基酸（例如羟脯氨酸，甘氨酸，精氨酸和赖氨酸）相关解释F3的生物活性。因此，超滤可用于改善鱿鱼胶原蛋白水解物的某些生物活性。

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