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Numerical study of heat transfer and blood flow in two-layered porous liver tissue during microwave ablation process using single and double slot antenna

机译:单缝和双缝天线在微波消融过程中两层多孔肝组织传热和血流的数值研究

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Microwave ablation (MWA) is a process that uses the heat from microwave energy to kill cancer cells without damaging the surrounding tissue. MWA is emerging as an attractive modality for thermal therapy of large soft tissue targets in short periods of time, making it particularly suitable for ablation of liver cancer. The effectiveness of this technique is related to the temperature achieved during the process, as well as the input microwave power and heating time of treatment. The models of heat and blood flow transport have been used extensively in the study of MWA process and a strong tool for predicting the temperature profile, blood velocity profile and coagulation zone. These models play important role in the optimization of devices and economical way to evaluate new hypothetical designs. Furthermore, they can be used as a guideline for the practical treatment. In this work, the interstitial MWA in two-layered porous liver by single slot microwave coaxial antenna (MCA) and double slot MCA is carried out. A complete mathematical model of MWA of the porous media approach is proposed, which uses transient momentum equations (Brinkman model extended Darcy model) and energy equation coupled with electromagnetic wave propagation equation to describe the specific absorption rate (SAR) profile, temperature profile and blood velocity profile within the porous liver. The coupled nonlinear set of these equations is solved using the axisymmetric finite element method (FEM). The role of transport phenomena in two layers porous media (layers of tumor and normal tissue) for advancing the progress in biomed-ical applications is investigated numerically. The study aims to understand of the influences of antenna type on the SAR profile, temperature profile and blood velocity profile. In particular, the results calculated from a porous media model are compared with the results calculated from a bioheat model as well as the experimental results from previous work in order to show the validity of the numerical results. The results show that the maximum SAR, temperature and blood velocity appears within the porous liver when using a single slot MCA which is higher than when using a double slot antenna. However, the volumetric SAR, temperature and blood velocity profile within the porous liver when using a double slot MCA provides a wider region in porous liver around the slot MCA and has two hot spot zones which occurs in the vicinity of these double slots.
机译:微波消融(MWA)是一种利用微波能量产生的热量杀死癌细胞而不会破坏周围组织的过程。 MWA逐渐成为一种在短时间内对大型软组织靶进行热疗的有吸引力的方式,使其特别适合于肝癌的消融。该技术的有效性与过程中达到的温度以及输入的微波功率和处理的加热时间有关。热和血流传输模型已广泛用于MWA过程的研究中,并且是预测温度曲线,血液速度曲线和凝血区的强大工具。这些模型在设备优化和评估新假设设计的经济方式中起着重要作用。此外,它们可以用作实际治疗的指南。在这项工作中,通过单缝微波同轴天线(MCA)和双缝MCA在两层多孔肝脏中进行了间质性MWA。提出了一个完整的多孔介质方法MWA数学模型,该模型利用瞬态动量方程(Brinkman模型扩展达西模型)和能量方程与电磁波传播方程相结合来描述比吸收率(SAR)曲线,温度曲线和血液。多孔肝脏内的速度分布。这些方程的耦合非线性集使用轴对称有限元法(FEM)求解。数值研究了两层多孔介质(肿瘤和正常组织的层)中传输现象对促进生物医学应用进展的作用。该研究旨在了解天线类型对SAR轮廓,温度轮廓和血流速度轮廓的影响。特别地,将从多孔介质模型计算出的结果与从生物热模型计算出的结果以及先前工作的实验结果进行比较,以证明数值结果的有效性。结果表明,当使用单缝隙MCA时,最大的SAR,温度和血流速度出现在多孔肝内,这比使用双缝隙天线时要高。但是,当使用双缝MCA时,多孔肝脏内的体积SAR,温度和血流速度分布在缝MCA周围的多孔肝脏中提供了较宽的区域,并在两个双缝附近出现了两个热点区域。

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