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首页> 外文期刊>International Journal of Heat and Mass Transfer >Indirect heating strategy for laser induced hyperthermia: An advanced thermal model
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Indirect heating strategy for laser induced hyperthermia: An advanced thermal model

机译：激光热疗的间接加热策略：高级热模型

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摘要

A novel heating strategy based on laser irradiation of surrounding tissues as an alternative to direct irradiation of superficial tumors is proposed and analyzed for the first time. The computational analysis is based on two-dimensional axisymmetric models for both radiative transfer and transient heat transfer in the human body. A diffuse component of the radiation field is calculated using P_1 approximation. Coupled transient energy equations and kinetic equations for composite human tissue take into account the metabolic heat generation and heat conduction, blood perfusion through capillaries, the volumetric heat transfer between arterial blood and tissue, the thermal conversions in blood and tumor tissue, the periodic laser heating, and also heat exchange between a human body and ambient medium. An example problem for a superficial human cancer has been solved numerically to illustrate the relative role of the problem parameters on the transient temperature field during hyperthermia treatment. In particular, the effect of embedded gold nanoshells which strongly absorb the laser radiation is analyzed. It is shown that required parameters of tumor hyperthermia can be also reached without gold nanoshells.
机译：首次提出并分析了一种基于周围组织激光照射的替代加热方法，以替代对浅表肿瘤的直接照射。计算分析基于二维轴对称模型，用于人体中的辐射传递和瞬态热传递。使用P_1近似计算辐射场的扩散分量。复合人体组织的耦合瞬态能量方程和动力学方程考虑了代谢热的产生和热传导，通过毛细血管的血液灌注，动脉血液与组织之间的体积热传递，血液与肿瘤组织中的热转化，周期性的激光加热以及人体与周围介质之间的热交换。数值解决了一个浅表人类癌症的示例问题，以说明问题参数在高温治疗过程中对瞬态温度场的相对作用。特别地，分析了强烈吸收激光辐射的嵌入式金纳米壳的作用。结果表明，没有金纳米壳也可以达到肿瘤热疗所需的参数。

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