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首页> 外文期刊>International journal of quality, statistics, & reliability >Physicochemical Characterization of Alginate Beads Containing Sugars and Biopolymers
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Physicochemical Characterization of Alginate Beads Containing Sugars and Biopolymers

机译：含糖和生物聚合物的藻酸盐珠的理化特性

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摘要

Alginate hydrogels are suitable for the encapsulation of a great variety of biomolecules. Several alternatives to the conventional alginate formulation are being studied for a broad range of biotechnological applications; among them the addition of sugars and biopolymers arises as a good and economic strategy. Sugars (trehalose and β-cydodextrin), a cationic biopolymer (chitosan), an anionic biopolymer (pectin), and neutral gums (Arabic, guar, espina corona, and vinal gums) provided different characteristics to the beads. Here we discuss the influence of beads composition on several physicochemical properties, such as size and shape, analyzed through digital image analysis besides both water content and activity. The results showed that the addition of a second biopolymer, β-CD, or trehalose provoked more compact beads, but the fact that they were compact not necessarily implies a concomitant increase in their circularity. Espina corona beads showed the highest circularity value, being useful for applications which require a controlled and high circularity, assuring quality control. Beads with trehalose showed lower water content than the rest of the system, followed by those containing galactomannans (espina corona, vinal, and guar gums), revealing polymer structure effects. A complete characterization of the beads was performed by FT-IR, assigning the characteristics bands to each individual component.
机译：海藻酸盐水凝胶适合于封装多种生物分子。对于广泛的生物技术应用，正在研究几种常规藻酸盐制剂的替代品。其中，添加糖和生物聚合物是一种很好的经济策略。糖（海藻糖和β-环糊精），阳离子生物聚合物（壳聚糖），阴离子生物聚合物（果胶）和中性树胶（阿拉伯树胶，瓜尔豆，espina日冕和牛至树胶）为珠子提供了不同的特性。在这里，我们讨论了珠子组成对几种物理化学性质（如大小和形状）的影响，除了水含量和活性外，还通过数字图像分析对其进行了分析。结果表明，添加第二种生物聚合物，β-CD或海藻糖会产生更致密的珠子，但是它们很致密的事实并不一定意味着其圆度会随之增加。 Espina电晕珠显示出最高的圆形度值，可用于需要可控和高圆形度的应用中，以确保质量控制。含有海藻糖的珠子的水含量低于系统中其余部分，其次是含有半乳甘露聚糖的珠子（espina corona，主干和瓜尔豆胶），显示出聚合物结构效应。磁珠的完整表征通过FT-IR进行，将特征带分配给每个单独的组件。

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  • 来源
    《International journal of quality, statistics, & reliability》 |2016年第2016期|9184039.1-9184039.7|共7页
  • 作者

    Tatiana Aguirre Calvo; Patricio Santagapita;

  • 作者单位

    Industry Department and Organic Chemistry Department, Faculty of Exact and Natural Sciences, University of Buenos Aires (FCEN-UBA), Buenos Aires, Argentina;

    Industry Department and Organic Chemistry Department, Faculty of Exact and Natural Sciences, University of Buenos Aires (FCEN-UBA), Buenos Aires, Argentina,National Council of Scientific and Technical Research (CONICET), Buenos Aires, Argentina;

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