Intrahost Selection of Plasmodium falciparum pfmdr1 Alleles after Antimalarial Treatment on the Northwestern Border of Thailand

Anne-Catrin Uhlemann1 Rose McGready23 Elizabeth A. Ashley23 Alan Brockman35 Pratap Singhasivanon4 Sanjeev Krishna1 Nicholas J. White24 Fran?ois Nosten23 and Ric N. Price25

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Intrahost Selection of Plasmodium falciparum pfmdr1 Alleles after Antimalarial Treatment on the Northwestern Border of Thailand

机译：泰国西北边界抗疟治疗后恶性疟原虫pfmdr1等位基因的宿主内选择

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BackgroundIncreased pfmdr1 copy number is associated with reduced susceptibility to structurally unrelated antimalarial drugs. We assessed how administration of different antimalarial drugs altered pfmdr1 polymorphism in parasites from patients who experienced treatment failure

机译：背景pfmdr1拷贝数增加与对结构无关的抗疟药的敏感性降低有关。我们评估了不同抗疟药的施用如何改变经历治疗失败的患者体内寄生虫的pfmdr1多态性

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来源
《Journal of Infectious Diseases》 |2007年第1期|134-141|共8页
作者
Anne-Catrin Uhlemann1 Rose McGready23 Elizabeth A. Ashley23 Alan Brockman35 Pratap Singhasivanon4 Sanjeev Krishna1 Nicholas J. White24 Fran?ois Nosten23 and Ric N. Price25;
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Centre for Infection Division of Cellular and Molecular Medicine St. George’s University of London London and;

Centre for Clinical Vaccinology and Tropical Medicine Churchill Hospital Headington Oxford United Kingdom;

Shoklo Malaria Research Unit Tak Province and;

Faculty of Tropical Medicine Mahidol University Bangkok Thailand;

Menzies School of Health Research Charles Darwin University Darwin Australia;

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1. Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand. [J] . Uhlemann AC, McGready R, Ashley EA, The Journal of Infectious Diseases . 2007,第1期

机译：在泰国西北边界进行抗疟处理后，恶性疟原虫pfmdr1等位基因的宿主内选择。
2. CYP2C8 status of patients with malaria influences selection of Plasmodium falciparum pfmdr1 alleles after amodiaquine-artesunate treatment. [J] . Isa Cavaco, Andreas M?rtensson, Gabrielle Fr?berg, The Journal of Infectious Diseases . 2013,第4期

机译：疟疾患者的CYP2C8状态会影响阿莫地喹-青蒿琥酯治疗后恶性疟原虫pfmdr1等位基因的选择。
3. CYP2C8 status of patients with malaria influences selection of Plasmodium falciparum pfmdr1 alleles after amodiaquine-artesunate treatment. [J] . Isa Cavaco, Andreas M?rtensson, Gabrielle Fr?berg, The Journal of Infectious Diseases . 2013,第4期

机译：CYP2C8疟疾患者的状态影响疟原虫治疗后疟原虫PFMDR1等位基因的选择。
4. THE EFFECT OF CHLOROQUINE AND RELATED ANTIMALARIALS ON HAEM IN Plasmodium falciparum [C] . J. M. Combrinck, T. E. Mabotha, K. K. Ncokazi, Annual Conference of the Microscopy Society of Southern Africa . 2012

机译：氯喹及相关抗疟药在疟原虫疟原虫中杂草的影响
5. Role of the pfmdr1 gene in Plasmodium falciparum resistance to antimalarial treatment [D] . Bohorquez, Elaine Brooks 2012

机译：pfmdr1基因在恶性疟原虫抗疟疾治疗中的作用
6. Intrahost Selection of Plasmodium falciparum pfmdr1 Alleles after Antimalarial Treatment on the Northwestern Border of Thailand [O] . Anne-Catrin Uhlemann, Rose McGready, Elizabeth A. Ashley, -1

机译：泰国西北边界抗疟治疗后恶性疟原虫pfmdr1等位基因的宿主内选择
7. Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand. [O] . Uhlemann, AC, Mcgready, R, Ashley, EA, 2007

机译：在泰国西北边境进行抗疟治疗后，恶性疟原虫pfmdr1等位基因的宿主内选择。

Intrahost Selection of Plasmodium falciparum pfmdr1 Alleles after Antimalarial Treatment on the Northwestern Border of Thailand

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