Immunization with a Tetraepitopic Lipid Core Peptide Vaccine Construct Induces Broadly Protective Immune Responses against Group A Streptococcus

Colleen Olive; Mei-Fong Ho; Joanne Dyer; Douglas Lincoln; Nadia Barozzi; Istvan Toth; and Michael F. Good

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Immunization with a Tetraepitopic Lipid Core Peptide Vaccine Construct Induces Broadly Protective Immune Responses against Group A Streptococcus

机译：四表位脂质核心肽疫苗构建体免疫诱导针对A组链球菌的广泛保护性免疫反应。

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BackgroundThe development of a vaccine to prevent infection with group A streptococcus (GAS) is hampered by the widespread diversity of circulating GAS strains and M protein types, and it is widely believed that a multivalent vaccine would provide better protective immunity

机译：背景技术循环GAS菌株和M蛋白类型的广泛多样性阻碍了预防A组链球菌（GAS）感染的疫苗的开发，并且广泛认为多价疫苗将提供更好的保护性免疫

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《Journal of Infectious Diseases》 |2006年第12期|1666-1676|共11页
作者
Colleen Olive; Mei-Fong Ho; Joanne Dyer; Douglas Lincoln; Nadia Barozzi; Istvan Toth; and Michael F. Good;
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Cooperative Research Centre for Vaccine Technology Queensland Institute of Medical Research and;

School of Molecular and Microbial Sciences and School of Pharmacy University of Queensland Brisbane Australia;

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1. Immunization with a tetraepitopic lipid core peptide vaccine construct induces broadly protective immune responses against group A streptococcus. [J] . Olive C, Ho MF, Dyer J, The Journal of Infectious Diseases . 2006,第12期

机译：用四表位脂质核心肽疫苗构建体免疫可诱导针对A组链球菌的广泛保护性免疫应答。
2. Intramuscular primary immunization by nucleic acid vaccine pcDNA/Gpd-IL-2 and enhanced immunization with mucosal adjuvant CpG-ODN and Gpd-IL-2 recombinant protein effectively induced strong mucosal immune responses and immune protective effects against Treponema pallidum skin infection [J] . Zhang Xiaohong, Zhao Tie, Zeng Tiebing, Experimental and therapeutic medicine . 2018,第3aPta1期

机译：核酸疫苗PCDNA / GPD-IL-2的肌内初级免疫和用粘膜佐剂CPG-ODN和GPD-IL-2重组蛋白的增强免疫有效地诱导了针对蛋白酶Pallidum皮肤感染的强粘膜免疫应答和免疫保护作用
3. Group A streptococcal vaccine delivery by immunization with a self-adjuvanting M protein-based lipid core peptide construct. [J] . Olive C, Batzloff M, Horvath A, The Indian journal of medical research. . 2004,第Suppla5期

机译：通过使用自佐剂的基于M蛋白的脂质核心肽构建体进行免疫接种来递送A组链球菌疫苗。
4. MULTI-EPITOPIC LIPID CORE PEPTIDE VACCINE WITH BROAD PROTECTIVE IMMUNE RESPONSES AGAINST GROUP A STREPTOCOCCUS [C] . Yoshio Fujita, Abu Baker M. Abdel-Aal, Pavla Simerska the European Peptide Symposium . 2007

机译：具有宽保护免疫反应的多集脂核肽疫苗对A组链球菌
5. Characterization of a protective systemic anticryptococcal immune response induced by mucosal immunization with heat-killed Cryptococcus neoformans yeast cells and analysis of a non-human primate model of cryptococcosis. [D] . McCracken, James P. 2006

机译：通过热灭活的新隐球菌酵母细胞的粘膜免疫诱导的保护性系统性抗隐球菌免疫应答的表征，以及非人灵长类隐球菌模型的分析。
6. Intramuscular primary immunization by nucleic acid vaccine pcDNA/Gpd-IL-2 and enhanced immunization with mucosal adjuvant CpG-ODN and Gpd-IL-2 recombinant protein effectively induced strong mucosal immune responses and immune protective effects against Treponema pallidum skin infection [O] . Xiaohong Zhang, Tie Zhao, Tiebing Zeng, -1

机译：核酸疫苗pcDNA / Gpd-IL-2的肌内一次免疫以及粘膜佐剂CpG-ODN和Gpd-IL-2重组蛋白的增强免疫有效诱导了强烈的粘膜免疫反应和针对梅毒螺旋体皮肤感染的免疫保护作用
7. Immunization with a Tetraepitopic Lipid Core Peptide Vaccine Construct Induces Broadly Protective Immune Responses against Group A Streptococcus [O] . Olive, Colleen, Ho, Mei-Fong, Dyer, Joanne, 2006

机译：四表位脂质核心肽疫苗构建体免疫诱导对A组链球菌的广泛保护性免疫反应。
8. Protective Immunity to Hepatitis B and Streptococcus Pneumoniae in Active Duty Women Versus Men: Prevalence and Responses to Preventive Immunization. [R] . Engler, R. J. 1996

机译：活动期女性与男性对乙型肝炎和肺炎链球菌的保护性免疫：预防性免疫的流行和反应。

Immunization with a Tetraepitopic Lipid Core Peptide Vaccine Construct Induces Broadly Protective Immune Responses against Group A Streptococcus

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