• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Autism and Developmental Disorders >Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II
【24h】

Maternal Early Life Factors Associated with Hormone Levels and the Risk of Having a Child with an Autism Spectrum Disorder in the Nurses Health Study II

机译：在护士健康研究中，与激素水平相关的孕产妇早期生活因素以及患有自闭症谱系障碍的儿童的风险II

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

It is not known whether reproductive factors early in the mother’s life influence risk of autism spectrum disorders (ASD). We assessed maternal age at menarche, menstrual cycle characteristics during adolescence, oral contraceptive use prior to first birth, body shape, and body mass index (BMI) in association with ASD using binomial regression in a cohort study of 61,596 women, including 743 cases. Overall, early life factors were not associated with ASD, though early age at menarche (RR for age 10 or less = 1.54, 95% CI 1.18, 2.02, p = 0.0002) and BMI at age 18 of ≥30 (RR 2.03, 95% CI 1.34, 3.08, p = 0.0008) were significantly associated with increased risk of ASD. Further work should investigate the potential influence of these factors.
机译：尚不清楚母亲生命初期的生殖因素是否会影响自闭症谱系障碍（ASD）的风险。在一项对61,596名妇女（包括743例）的队列研究中，我们使用二项式回归评估了初潮时的产妇年龄，青春期的月经周期特征，首次分娩前口服避孕药，体形和体重指数（BMI）与ASD的关系。总体而言，尽管初潮的早期年龄（10岁以下的RR = 1.54，95％CI 1.18，2.02，p = 0.0002）和18岁的BMI≥30（RR 2.03，95），但早期生活因素与ASD无关。 ％CI 1.34，3.08，p = 0.0008）与ASD风险增加显着相关。进一步的工作应调查这些因素的潜在影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号