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首页> 外文期刊>Journal of Autism and Developmental Disorders >Neuropsychological Functioning of Siblings of Children with Autism, Siblings of Children with Developmental language Delay, and Siblings of Children with Mental Retardation of Unknown Genetic Etiology
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Neuropsychological Functioning of Siblings of Children with Autism, Siblings of Children with Developmental language Delay, and Siblings of Children with Mental Retardation of Unknown Genetic Etiology

机译：自闭症儿童的兄弟姐妹，发育语言延迟儿童的兄弟姐妹以及未知遗传病因的智力低下儿童的兄弟姐妹的神经心理学功能

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摘要

Neuropsychological functioning of 30 siblings of children with autism (AU-S), 28 siblings of children with mental retardation of (MR-S), and 30 siblings of children with developmental language delay (DLD-S) was compared. Two siblings, both AU-S, received diagnoses of pervasive developmental disorder (PDD). More siblings with cognitive disabilities were found in DLD-S than in AU-S. However, these differences disappeared after excluding diagnosed siblings or after accounting for family membership. In sum, despite the elevated incidence of PDD among AU-S, the neuropsychological functioning of the remaining siblings did not convey specific characteristics related to the genetic risk associated with autism, in contrast to the cognitive functioning of the DLD-S, which did reflect a genetic risk.
机译：比较了30名自闭症儿童兄弟姐妹（AU-S），28名智障儿童兄弟姐妹（MR-S）和30名发育语言延迟儿童兄弟姐妹（DLD-S）的神经心理功能。两个兄弟姐妹（均为AU-S）均被诊断出患有广泛性发育障碍（PDD）。在DLD-S中发现的认知障碍兄弟姐妹多于AU-S。但是，这些差异在排除已诊断的同胞或考虑了家庭成员身份后消失了。总之，尽管AU-S中PDD的发病率升高，但是与DLD-S的认知功能相反，其余兄弟姐妹的神经心理学功能并未传达与自闭症相关的遗传风险相关的特定特征。遗传风险。

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