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首页> 外文期刊>Journal of Autism and Developmental Disorders >Abnormal Brain Lateralization in High-Functioning Autism
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Abnormal Brain Lateralization in High-Functioning Autism

机译：高功能自闭症的异常脑侧位化

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摘要

Disturbances in lateral preference in autism are of interest because of their potential to shed light on brain maturational processes in this disorder. Forty-seven autistic individuals with a history of disordered early language development and 22 autistic individuals with normal early language acquisition were matched with 112 healthy individuals and compared on a standardized measure of lateral preference, the Edinburgh Handedness Inventory. Autistic individuals with a history of early language disturbance showed more atypical cerebral dominance than both healthy participants and autistic individuals with normal early language skills. The data indicated maturational disturbances in establishing lateral preference rather than increased rates of left handedness. Atypical establishment of cerebral dominance may be one cause of disordered language development in autism.
机译：自闭症的侧向偏好障碍是令人关注的，因为它们有可能揭示这种障碍的大脑成熟过程。将具有早期语言发展障碍史的47名自闭症患者和具有正常早期语言习得的22名自闭症患者与112名健康个体进行匹配，并根据横向偏爱的标准量度（爱丁堡习惯清单）进行比较。有早期语言障碍史的自闭症患者比健康参与者和具有正常早期语言能力的自闭症患者表现出更多的非典型大脑优势。数据表明，在建立侧向偏好而不是增加左撇子率方面存在成熟障碍。非典型的大脑优势地位可能是自闭症语言发展紊乱的原因之一。

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