• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Autism and Developmental Disorders >Efficacy of Porcine Secretin in Children with Autism and Pervasive Developmental Disorder
【24h】

Efficacy of Porcine Secretin in Children with Autism and Pervasive Developmental Disorder

机译：猪促胰液素对自闭症和普遍性发育障碍儿童的疗效

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Secretin, a gastrointestinal (GI) hormone, was reported in a preliminary study to improve language and behavior in children with autism/pervasive developmental disorder (PDD) and chronic diarrhea. To determine the efficacy of secretin, we completed a double-blind, placebo-controlled, crossover (3 weeks) study in children with autism/PDD and various GI conditions using a single dose of intravenous porcine secretin. Children with chronic, active diarrhea showed a reduction in aberrant behaviors when treated with the secretin but not when treated with the placebo. Children with no GI problems are unaffected by either secretin or placebo. The improvement seen with secretin in children with autism/PDD and chronic diarrhea suggests that there may be a subtype of children with autism/PDD who respond to secretin.
机译：一项初步研究报道了一种胃肠道（GI）激素Secretin，可改善自闭症/普遍性发育障碍（PDD）和慢性腹泻儿童的语言和行为。为了确定促胰液素的功效，我们使用单剂量的静脉内猪促胰液素完成了一项针对自闭症/ PDD和各种胃肠疾病的儿童的双盲，安慰剂对照，交叉试验（3周）。患有慢性活动性腹泻的儿童在用促胰液素治疗时表现出异常的行为减少，而在用安慰剂治疗时则没有。没有胃肠道问题的儿童不会受到促胰液素或安慰剂的影响。自闭症/ PDD和慢性腹泻患儿的促胰液素水平有所改善，这表明自闭症/ PDD患儿可能会对促胰液素产生反应。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号