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Development of a first-generation miniature multiple reference optical coherence tomography imaging device

机译:第一代微型多参考光学相干断层扫描成像设备的开发

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摘要

Multiple reference optical coherence tomography (MR-OCT) is a technology ideally suited to low-cost, compact OCT imaging. This modality is an extension of time-domain OCT with the addition of a partial mirror in front of the reference mirror. This enables extended, simultaneous depth scanning with the relatively short scan range of a miniature voice coil motor on which the scanning mirror is mounted. This work details early stage development of the first iteration of a miniature MR-OCT device. This iteration utilizes a fiber-coupled input from an off-board superluminescent diode. The dimensions of the module are 40 × 57 mm. Off-the-shelf miniature optical components, voice coil motors, and photodetectors are used, with the complexity of design depending on the specific application. The photonic module can be configured as either polarized or nonpolarized and can include balanced detection. The results shown in this work are from the nonpolarized device. The system was characterized through measurement of the input spectrum, axial resolution, and signal-to-noise ratio. Typical B-scans of static and in vivo samples are shown, which illustrate the potential applications for such a technology.
机译:多参考光学相干断层扫描(MR-OCT)是非常适合低成本,紧凑型OCT成像的技术。这种方式是时域OCT的扩展,在参考镜的前面增加了部分镜。这使得能够在安装扫描镜的微型音圈电机的相对短的扫描范围内进行扩展的,同时的深度扫描。这项工作详细介绍了微型MR-OCT设备第一次迭代的早期开发。该迭代利用了板外超发光二极管的光纤耦合输入。模块的尺寸为40×57毫米。使用了现成的微型光学组件,音圈电机和光电探测器,具体设计取决于具体应用。光子模块可以配置为偏振或非偏振,并且可以包括平衡检测。这项工作中显示的结果来自非极化设备。通过测量输入光谱,轴向分辨率和信噪比对系统进行了表征。显示了静态和体内样品的典型B扫描图,这些图说明了这种技术的潜在应用。

著录项

  • 来源
    《Journal of biomedical optics》 |2016年第12期|126020.1-126020.7|共7页
  • 作者单位

    National University of Ireland, School of Physics, Tissue Optics and Microcirculation Imaging Group, National Biophotonics and Imaging Platform,Galway H91 CF50, Ireland,Compact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States;

    National University of Ireland, School of Physics, Tissue Optics and Microcirculation Imaging Group, National Biophotonics and Imaging Platform,Galway H91 CF50, Ireland,Compact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States;

    Irish Photonic Integration Centre (IPIC), Tyndall National Institute, Lee Maltings Complex, Dyke Parade, Cork T12 R5CP, Ireland;

    Irish Photonic Integration Centre (IPIC), Tyndall National Institute, Lee Maltings Complex, Dyke Parade, Cork T12 R5CP, Ireland;

    Irish Photonic Integration Centre (IPIC), Tyndall National Institute, Lee Maltings Complex, Dyke Parade, Cork T12 R5CP, Ireland;

    Compact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States;

    Compact Imaging Inc., 897 Independence Avenue, Suite 5B, Mountain View, California 94043, United States;

    National University of Ireland, School of Physics, Tissue Optics and Microcirculation Imaging Group, National Biophotonics and Imaging Platform,Galway H91 CF50, Ireland;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    multiple reference optical coherence tomography; miniature optical systems; low cost; portable; low coherence; biometrics;

    机译:多参考光学相干断层扫描;微型光学系统;低成本;便携式相干性低生物识别;

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