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首页> 外文期刊>Journal of biomedical optics >Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers:preliminary study for determination of optimal parameters
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Closure of skin incisions by laser-welding with a combination of two near-infrared diode lasers:preliminary study for determination of optimal parameters

机译：通过结合两个近红外二极管激光器进行激光焊接来闭合皮肤切口：确定最佳参数的初步研究

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摘要

Laser welding has the potential to become an effective method for wound closure and healing without sutures. Closure of skin incisions by laser welding with a combination of two near-infrared lasers (980 and 1064 nm), was performed for the first time in this study. One centimeter long, full-thickness incisions were made on the Wistar rat's dorsal skin. The efficiencies of laser-welding with different parameters were investigated. Incision-healing, histology examination, and a tensile strength test of incisions were recorded. Laser welding with the irradiance level of 15.9 W/cm~2 for both 980 and 1064-nm lasers and exposure time of 5 s per spot in continuous wave mode yielded a more effective closure and healing with minimal thermal damage, faster recovery, and stronger apposition in comparison with a suturing technique. The conclusion is that skin welding with a combination of two near-infrared diode lasers can be a good candidate for incision closure, and further investigations are in progress for clinical Use.
机译：激光焊接有望成为一种无需缝合即可闭合和愈合伤口的有效方法。在这项研究中，首次通过结合两个近红外激光（980和1064 nm）进行激光焊接来闭合皮肤切口。在Wistar大鼠的背部皮肤上做一个1厘米长的全层切口。研究了不同参数的激光焊接效率。记录切口愈合，组织学检查和切口拉伸强度测试。 980和1064 nm激光的辐照度水平均为15.9 W / cm〜2的激光焊接，连续波模式下每个点的曝光时间为5 s，可以实现更有效的闭合和愈合，并具有最小的热损伤，恢复更快且强度更高与缝合技术相比。结论是，结合两个近红外二极管激光器的皮肤焊接可以作为切口闭合的良好候选者，并且正在进行临床研究的进一步研究。

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  • 来源
    《Journal of biomedical optics》 |2011年第3期|p.172-178|共7页
  • 作者

    Liming Hu; Zhihua Lu; Biao Wang; Junsheng Cao; Xiaobo Ma; Zhenhua Tian; Zhijian Gao; Li Qin; Xiaodong Wu; Yun Liu; Lijun Wang;

  • 作者单位

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China,Craduate School of the Chinese Academy of Sciences, Beijing, 10049, China;

    First Hospital of Jilin University, Urologic Department, No. 71 Xinmin Street, Changchun City, 130021, China;

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China;

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China;

    First Hospital of Jilin University, Pathologic Department, No. 71 Xinmin Street, Changchun City, 130021, China;

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China,Craduate School of the Chinese Academy of Sciences, Beijing, 10049, China;

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China;

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China;

    Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Laboratory of Medical Laser Technology, CAS, No. 14, Longshan Road, Suzhou New District, Suzhou City, 215163, China;

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China;

    Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences, Laboratory of Excited State Processes, CAS, No. 3888 SE Lake Road, Changchun City, 130033, China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    tissue welding; skin closure; diode laser; tensile strength; wound healing.;

    机译：组织焊接;皮肤封闭二极管激光器抗拉强度;伤口愈合。;

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