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Aberrant expression of intelectin-1 in gastric cancer: its relationship with clinicopathological features and prognosis

机译:intelectin-1在胃癌中的异常表达及其与临床病理特征和预后的关系

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摘要

Human intelectin-1 (ITLN-1) is a novel identified galactose-binding lectin that is expressed in the colonic goblet cells. Since gastric adenocarcinomas can arise through a process of intestinalization, we speculate that ITLN-1 may be aberrantly expressed in gastric cancer. This study was undertaken to examine the ITLN-1 expression in gastric cancer and correlate it with clinical outcomes.
机译:人intelectin-1(ITLN-1)是一种新型鉴定的半乳糖结合凝集素,在结肠杯状细胞中表达。由于胃腺癌可通过肠化过程产生,因此我们推测ITLN-1可能在胃癌中异常表达。进行这项研究以检查ITLN-1在胃癌中的表达并将其与临床结果相关联。

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  • 来源
    《Journal of Cancer Research and Clinical Oncology》 |2012年第1期|p.163-172|共10页
  • 作者单位

    Department of Pathology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, People’s Republic of China;

    Department of Pathology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, People’s Republic of China;

    Department of Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, People’s Republic of China;

    Department of Surgery, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, People’s Republic of China;

    Department of Pathology, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei Province, People’s Republic of China;

    Department of Gastroenterology, Union Ho;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Intelectin-1; Gastric cancer; Gene expression; Prognosis;

    机译:Intelectin-1;胃癌;基因表达;预后;

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