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首页> 外文期刊>Journal of Clinical and Experimental Neuropsychology >Higher education is not associated with greater cortical thickness in brain areas related to literacy or intelligence in normal aging or mild cognitive impairment
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Higher education is not associated with greater cortical thickness in brain areas related to literacy or intelligence in normal aging or mild cognitive impairment

机译：高等教育与正常衰老或轻度认知障碍中识字或智力相关的大脑区域更大的皮质厚度无关

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摘要

Education may reduce risk of dementia through passive reserve, by increasing neural substrate. We tested the hypotheses that education is associated with thicker cortex and reduced rates of atrophy in brain regions related to literacy and intellectual ability. Healthy older adults and those with mild cognitive impairment were categorized into high (≥18 years) and low (≤13 years) education groups. Higher education was associated with thinner cortices in several areas, but one-year atrophy rates in these areas did not differ by education group. These results do not support a passive reserve model in which early-life education protects against dementia by increasing cortical thickness. Connectivity and synaptic efficiency or other lifestyle factors may more directly reflect cognitive reserve.View full textDownload full textKeywordsBrain reserve, Cortical thickness, Education, Literacy, Hippocampal volume, Mild cognitive impairment, AgingRelated var addthis_config = { ui_cobrand: "Taylor & Francis Online", services_compact: "citeulike,netvibes,twitter,technorati,delicious,linkedin,facebook,stumbleupon,digg,google,more", pubid: "ra-4dff56cd6bb1830b" }; Add to shortlist Link Permalink http://dx.doi.org/10.1080/13803395.2012.702733
机译：通过增加神经底物，教育可以通过被动储备来降低痴呆症的风险。我们检验了以下假设：教育与较厚的皮质和与识字和智力相关的大脑区域萎缩率降低相关。健康的老年人和轻度认知障碍者被分为高（≥18岁）和低（≥13岁）教育组。在一些地区，高等教育与皮层较薄有关，但这些地区的一年萎缩率因教育组而异。这些结果不支持被动储备模型，在该模型中，早期教育通过增加皮层厚度来预防痴呆。连通性和突触效率或其他生活方式因素可能更直接反映认知储备。查看全文下载全文关键词大脑储备，皮层厚度，教育程度，读写能力，海马体积，轻度认知障碍，衰老services_compact：“ citeulike，netvibes，twitter，technorati，美味，linkedin，facebook，stumbleupon，digg，google，更多”，发布：“ ra-4dff56cd6bb1830b”};添加到候选列表链接永久链接http://dx.doi.org/10.1080/13803395.2012.702733

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