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首页> 外文期刊>Journal of Computational Neuroscience >The unknown but knowable relationship between Presaccadic Accumulation of activity and Saccade initiation
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The unknown but knowable relationship between Presaccadic Accumulation of activity and Saccade initiation

机译:PresAccadic积累的未知但明确的关系与扫描开始

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摘要

The goal of this short review is to call attention to a yawning gap of knowledge that separates two processes essential for saccade production. On the one hand, knowledge about the saccade generation circuitry within the brainstem is detailed and precise - push-pull interactions between gaze-shifting and gaze-holding processes control the time of saccade initiation, which begins when omnipause neurons are inhibited and brainstem burst neurons are excited. On the other hand, knowledge about the cortical and subcortical premotor circuitry accomplishing saccade initiation has crystalized around the concept of stochastic accumulation - the accumulating activity of saccade neurons reaching a fixed value triggers a saccade. Here is the gap: we do not know how the reaching of a threshold by premotor neurons causes the critical pause and burst of brainstem neurons that initiates saccades. Why this problem matters and how it can be addressed will be discussed. Closing the gap would unify two rich but curiously disconnected empirical and theoretical domains.
机译:这次简短审查的目标是引起注意,对知识的打呵欠差距,将两种过程分开了扫视生产。一方面,关于脑干内的扫视产生电路的知识是详细且精确的 - 缩小和凝视的过程之间的预先推挽相互作用控制扫描扫描时间,从抑制无多变神经元并脑干爆发神经元开始很兴奋。另一方面,关于皮质和皮质波动的热量电路完成扫描启动的知识已经围绕随机累积的概念结晶 - 达到固定值的扫视神经元的累积活性触发扫视。这是差距:我们不知道首映神经元的阈值如何导致启动扫视的脑干神经元的关键暂停和爆发。为什么讨论此问题以及如何讨论如何解决。结束差距将统一两种富人但奇妙的经验和理论域。

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