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首页> 外文期刊>Journal of dairy research >Evaluation of different acute-phase proteins for herd health diagnostics in early postpartum Holstein Friesian dairy cows
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Evaluation of different acute-phase proteins for herd health diagnostics in early postpartum Holstein Friesian dairy cows

机译：产后产后群体健康诊断不同急性期蛋白的评价

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This research communication describes (1) the comparison of acute-phase protein (APP) concentrations in transition dairy cows on different farms using both pooled and individual blood samples, and (2) the association among different APP and clinical health parameters. The first hypothesis was that early postpartum dairy cows from different farms differ in the level of inflammation, which might be determined using APP assays in both pooled and individual blood samples. The second hypothesis was that the APP haptoglobin (Hp) might be the most sensitive parameter to detect cows at risk of excessive postpartum inflam-mation concomitant with systemic disease. Serum concentrations of Hp, serum amyloid-A (SAA), total protein (TP), albumin (Alb), coeruloplasmin (Cp) and C-reactive protein (CRP) in 100 fresh lactating cows (within 0-8 d postpartum) from 10 farms were compared and associated to clinical health parameters (rectal body temperature, vaginal discharge (Metricheck™ score), rumen fill, vulvovaginal laceration) using both pooled and individual blood samples. Mean serum concentrations of Hp, SAA and TP revealed significant differ-ences among farms. Pooled serum samples of farms showed high correlations with the mean of individual samples. Only Hp was significantly positively correlated to both body tem-perature and Metricheck™ score. In conclusion, Hp differentiates dairy farms regarding the inflammatory state of transition cows using individual and pooled serum samples within the first week postpartum. It also mirrors the individual degree of inflammation, thus proving to be a diagnostic parameter of high interest during the periparturient period.
机译：该研究通信描述了（1）使用池和个体血液样本的不同农场过渡乳制品奶牛的急性期蛋白（APP）浓度的比较，以及（2）不同应用和临床健康参数之间的关联。第一个假设是，来自不同农场的早期产后乳制品奶牛在炎症水平上不同，这可能在汇总和个体血液样本中使用APP测定来确定。第二个假设是App Haptoglobin（HP）可能是最敏感的参数，以检测患有过量的产后炎症的风险伴有全身疾病的奶牛。 HP，血清淀粉样蛋白-A（SAA），总蛋白质（TP），白蛋白（ALB），Coeruloplasmin（CP）和C-反应蛋白（CRP）的血清浓度（在0-8 d产后）中将10个农场进行比较，与临床健康参数（直肠体温，阴道分泌物（MetRiCheck™评分），瘤胃填充，外阴衰减撕裂）进行相关，使用汇总和个体血样。平均HP，SAA和TP的血清浓度显示出在农场之间的显着差异。合并的农场样品与个体样品的平均值显示出高的相关性。只有HP与身体TEM-CHERITION和METRICHECK™评分显着相关。总之，惠普将乳制品农场与第一个产后的第一周使用单独的血清样品进行过渡奶牛的炎症状态。它还反映了个体炎症程度，从而证明是在围剖视时期的高兴趣的诊断参数。

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