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首页> 外文期刊>Journal of dairy research >Comparison between two preventive treatments for hyperketonaemia carried out pre-portum: effects on non-esterified fatty acids, β-hydroxybutyrate and some biochemical parameters during peripartum and early lactation
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Comparison between two preventive treatments for hyperketonaemia carried out pre-portum: effects on non-esterified fatty acids, β-hydroxybutyrate and some biochemical parameters during peripartum and early lactation

机译：对胸腺预防术治疗的两种预防治疗的比较：胞胎和早期泌乳期间对非酯化脂肪酸，β-羟基丁酸酯和一些生化参数的影响

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摘要

The objective of this study was to compare the effect of two different preventive protocols, on serum β-hydroxybutyrate (BHB) concentration and liver health indices pre-partum and dur-ing early-lactation in high-yielding Holstein dairy cows. One hundred cows were randomly divided into three groups: control group (CTRL, n = 20, without preventive treatment), second group (SUPP, n = 40 animals treated with a compound based on acetyl-methionine, inositol, cyanocobalamin, 1-alanine, 1-arginine, 1-threonine, 1-glutamic acid supplementation and α-lipoic acid) and third group (MON, n =40 animals treated with monensin). Blood samples were collected from all cows at on 3 occasions pre-partum and 3 occasions post-partum. Body condition (BCS) score was evaluated and glucose, non-esterified fatty acids (NEFA), BHB, triglycerides, total cholesterol, alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyltransferase (GGT), total bilirubin, total proteins, globulins, albumin and urea concentrations were assessed. Two-way repeated measures analysis of variance was applied. Statistically significant differences among the three experimental groups were found in the values of all studied parameters (P<0.05). Our results confirm the established beneficial effect of MON treatment in decreasing BHB levels and increasing glucose availabil-ity after calving. Serum biochemical analysis revealed the expected post-partum alterations attributable to adaptations that influenced the metabolism and liver function in CTRL, whereas these alterations were reduced or absent in SUPP and MON. Results from the present study suggest that both preventive protocols, but in particular SUPP, could positively affect selected indicators of energy metabolism reducing the risk of hyperketonaemia and increase of liver function in Holstein dairy cows, both pre- and post-partum.
机译：本研究的目的是比较两种不同预防方案，对血清β-羟基丁酸酯（BHB）浓度和肝脏健康指数预粒度的效果，并在高产Holstein奶牛中进行早期哺乳期。将一批奶牛随机分为三组：对照组（Ctrl，N = 20，没有预防性处理），第二组（使用基于乙酰甲硫氨酸，肌醇，氰基胺，1-丙氨酸的化合物治疗的二组（Supp，N = 40只动物，1-精氨酸，1〜苏氨酸，1-谷氨酸补充剂和α-硫辛酸）和第三组（用MONENSIN处理的MON，N = 40只动物）。从所有奶牛收集血液样品在3场5场比赛中收集所有奶牛。评估身体状况（BCS）评分和葡萄糖，非酯化脂肪酸（NEFA），BHB，甘油三酯，总胆固醇，丙氨酸氨基转移酶（ALT），天冬氨酸氨基转移酶（AST），γ-谷氨酰胺转移酶（GGT），总胆红素，总共评估蛋白质，球蛋白，白蛋白和尿素浓度。应用双向反复措施的差异分析。在所有研究参数的值中发现了三个实验组之间的统计学显着差异（P <0.05）。我们的结果证实了Mon治疗在降低BHB水平中的既定有益效果，并在产犊后增加葡萄糖。血清生物化学分析揭示了预期的伴侣后改变，其适应影响了Ctrl中新陈代谢和肝功能，而这些改变是在谢谢和周一减少或不存在。本研究的结果表明，预防方案，但特别是Supp，可以积极影响所选能量代谢指标，降低霍尔斯坦奶牛的高蛋白质血症风险和肝脏功能的增加。

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  • 来源
    《Journal of dairy research》 |2021年第1期|38-44|共7页
  • 作者

    Enrico Fiore; Laura Perillo; Matteo Gianesella; Claudia Giannetto; Elisabetta Giudice; Giuseppe Piccione; Massimo Morgante;

  • 作者单位

    Department of Animal Medicine Productions and Health (MAPS) University of Padua Viale dell'Universita 16 35020 Legnaro (PD) Italy;

    Department of Veterinary Science University of Messina Polo Universitario dell'Annunziata 98168 Messina Italy;

    Department of Animal Medicine Productions and Health (MAPS) University of Padua Viale dell'Universita 16 35020 Legnaro (PD) Italy;

    Department of Veterinary Science University of Messina Polo Universitario dell'Annunziata 98168 Messina Italy;

    Department of Veterinary Science University of Messina Polo Universitario dell'Annunziata 98168 Messina Italy;

    Department of Veterinary Science University of Messina Polo Universitario dell'Annunziata 98168 Messina Italy;

    Department of Animal Medicine Productions and Health (MAPS) University of Padua Viale dell'Universita 16 35020 Legnaro (PD) Italy;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Cow; hyperketonaemia; lactation; liver; supplementation;

    机译：奶牛;超托管血症;哺乳;肝脏;补充;

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