trans-10, cis-12 Conjugated Linoleic Acid Decreases Lipogenic Rates and Expression of Genes Involved in Milk Lipid Synthesis in Dairy Cows

L.H. Baumgard; E. Matitashvili; B.A. Corl

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trans-10, cis-12 Conjugated Linoleic Acid Decreases Lipogenic Rates and Expression of Genes Involved in Milk Lipid Synthesis in Dairy Cows

机译：反式，顺式12共轭亚油酸降低产奶率和奶牛乳脂合成相关基因的表达

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Feeding conjugated linoleic acid (CLA) reduces milk fat synthesis in lactating dairy cows, and the effect has been shown to be specific for the trans-10, cis-12 CLA isomer. Our objectives were to examine potential mech- anisms by which trans-10, cis-12 CLA inhibits milk fat synthesis. Multiparous Holstein cows (n=4) in late lactation were used in a balanced 2×2 crossover design. Treatments consisted of a 5 d abomasal infusion of ei- Ther skim milk (control) or purified trans-10, cis-12 CLA (13.6 g/d) emulsified in skim milk.

机译：饲喂共轭亚油酸（CLA）会降低泌乳奶牛的乳脂合成，并且该作用已被证明对顺式10，顺式12 CLA异构体具有特异性。我们的目标是研究潜在的机制，即反式10，顺式12 CLA抑制乳脂合成。泌乳后期的多头荷斯坦奶牛（n = 4）用于平衡的2×2交叉设计。治疗方法为：在e-Ther脱脂乳（对照）或在脱脂乳中乳化的纯化的trans-10，cis-12 CLA（13.6 g / d）进行5 d乳腺肿瘤输液治疗。

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来源
《Journal of dairy science》 |2002年第9期|p.2155-2163|共9页
作者
L.H. Baumgard; E. Matitashvili; B.A. Corl;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类乳品加工工业;
关键词
conjugated linoleic acid; lactation; milk fat; milk fat depression;

机译：共轭亚油酸;哺乳期乳脂牛奶脂肪减少;

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1. Effect of trans-10, cis-12 conjugated linoleic acid (CLA) on expression of lipogenic genes is related to amount of trans-10, cis-12 CLA per unit of metabolic weight in lactating dairy ewes [J] . Oliveira D. E., Urio M., Sandri E. C. Small Ruminant Research . 2018,第期

机译：Trans-10，CIS-12缀合的亚油酸（CLA）对脂质基因表达的影响与哺乳酸乳制品母羊每单位代谢重量的Trans-10，CIS-12 CLA的量有关
2. Time-dependent effect of trans-10,cis-12 conjugated linoleic acid on gene expression of lipogenic enzymes and regulators in mammary tissue of dairy cows [J] . Harvatine Kevin J., Boisclair Y. R., Bauman Dale E. Journal of dairy science . 2018,第8期

机译：Trans-10，cis-12共轭亚油酸对奶牛乳腺组织中脂肪酶和调节因子基因表达的时间依赖性
3. Trans-10, cis-12 conjugated linoleic acid reduces milk fat content and lipogenic gene expression in the mammary gland of sows without altering litter performance [J] . Sandri E. C., Harvatine K. J., Oliveira D. E. The British Journal of Nutrition . 2020,第6期

机译：Trans-10，CIS-12共轭亚油酸在母猪的乳腺中减少了乳脂含量和脂质基因表达，而不改变垫料性能
4. Trans-10, cis-12 Conjugated Linoleic Acid Decreases Expression of Genes Involved in Mammary Lipid Metabolism in Dairy Goat [C] . Wei Zhang, Huaiping Shi, Jun Luo, 4th international symposium on dairy cow nutrition and milk quality proceedings . 2015

机译：Trans-10，cis-12共轭亚油酸降低了乳山羊乳脂代谢相关基因的表达。
5. Trans-10, cis-12 conjugated linoleic acid alters lipid metabolism and induces apoptosis in 3T3-L1 preadipocytes. [D] . Evans, Mary Elizabeth. 2001

机译：反式10，顺式12共轭亚油酸可改变脂质代谢并诱导3T3-L1前脂肪细胞凋亡。
6. JNK inhibition by SP600125 Attenuates Trans-10 Cis-12 Conjugated Linoleic Acid- Mediated Regulation of Inflammatory and Lipogenic Gene Expression [O] . Kristina Martinez, Arion Kennedy, Michael McIntosh -1

机译：通过SP600125抑制JNK抑制衰减反式10CIS-12共轭亚油酸介导的炎症和脂肪生成基因表达的调节
7. Trans-10, cis-12 conjugated linoleic acid decreases de novo lipid synthesis in human adipocytes [O] . Obsen, Thomas, Faergeman, Nils J, Chung, Soonkyu, 2012

机译：Trans-10，顺式12共轭亚油酸可减少人脂肪细胞中的从头脂质合成

trans-10, cis-12 Conjugated Linoleic Acid Decreases Lipogenic Rates and Expression of Genes Involved in Milk Lipid Synthesis in Dairy Cows

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