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首页> 外文期刊>Journal of Electronic Testing >Testing and Diagnosis of Realistic Defects in Digital Microfluidic Biochips
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Testing and Diagnosis of Realistic Defects in Digital Microfluidic Biochips

机译:数字微流控生物芯片中实际缺陷的测试和诊断

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摘要

Microfluidics-based biochips are soon expected to revolutionize biosensing, clinical diagnostics and drug discovery. Robust off-line and on-line test techniques are required to ensure system dependability as these biochips are deployed for safety-critical applications. Due to the underlying mixed-technology and mixed-energy domains, biochips exhibit unique failure mechanisms and defects. We first relate some realistic defects to fault models and observable errors. We next set up an experiment to evaluate the manifestations of electrode-short faults. Motivated by the experimental results, we present a testing and diagnosis methodology to detect catastrophic faults and locate faulty regions. The proposed method is evaluated using a biochip performing real-life multiplexed bioassays.
机译:基于微流体的生物芯片有望很快改变生物传感,临床诊断和药物发现的方式。由于这些生物芯片被部署用于安全关键型应用,因此需要可靠的离线和在线测试技术来确保系统的可靠性。由于潜在的混合技术领域和混合能源领域,生物芯片表现出独特的失效机制和缺陷。我们首先将一些现实的缺陷与故障模型和可观察到的错误联系起来。接下来,我们建立一个实验来评估电极短路故障的表现。根据实验结果,我们提出了一种检测和诊断方法,可以检测出灾难性故障并定位故障区域。使用执行实时多重生物测定的生物芯片评估提出的方法。

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