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首页> 外文期刊>Infection and immunity >Delayed-type hypersensitivity and immunoglobulin E in American cutaneous leishmaniasis.
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Delayed-type hypersensitivity and immunoglobulin E in American cutaneous leishmaniasis.

机译：延迟型超敏反应和免疫球蛋白E在美国皮肤leishManiaisis中。

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Delayed-type hypersensitivity (DTH) and both total and specific immunoglobulin E (IgE) antibody levels were studied during an outbreak of American cutaneous leishmaniasis. Direct correlations were detected between DTH reactivity and either age or the period of evolution of the infection, and a clear association with sex (strongest response in females) was observed. Extremely high, age-dependent, total serum IgE levels were measured in the study group, probably due to concurrent intestinal helminthiasis. A low proportion of the group also had detectable levels of specific anti-Leishmania IgE antibody. Total and specific IgE levels were also sex dependent (lowest in females), and an inverse correlation was found between these levels and DTH responsiveness, possibly reflecting the intervention of regulatory influences of T-lymphocyte activity.
机译：在美国皮肤皮肤爆发期间研究了延迟型超敏反应（DTH）和总和特异性免疫球蛋白E（IgE）抗体水平。在第三次反应性和感染的转化期间检测到直接相关性，并且观察到与性别（女性最强的反应）的明确关联。在研究组中测量了极高，年龄依赖性，总血清IgE水平，可能是由于同时肠道蠕虫症。该组的低比例也具有可检测的特异性抗利什曼IgE抗体水平。总和特异性的IgE水平也是性依赖性的（女性最低），并且在这些水平和DTH反应之间发现了反向相关性，可能反映了T淋巴细胞活性的监管影响的介入。

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