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首页> 外文期刊>Journal of environmental science and health >Ecotoxicological assessment of doxycycline in soil
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Ecotoxicological assessment of doxycycline in soil

机译：土壤中强力霉素的生态毒理学评估

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摘要

Doxycycline has been used in continually increasing quantities for mass treatment of food animals because of its greater bioavailability relative to older tetracyclines. The study presented in this paper was undertaken to investigate the degradation rate of the tetracycline derivative in manure-amended soil. In the present experiment, following composting, the doxycycline-contaminated manure was applied to agricultural land, and a field study was performed to investigate the degradation rate of doxycycline in soil. By the end of the 20-week sampling period, about 20 %, 33 % and 18 % of the initial doxycycline concentrations could be measured in soil samples taken at three different soil depths. The calculated half-life of doxycycline in the soil was 66.5, 76.3 and 59.4 days at depths of 0 cm, 25 cm and 50 cm, respectively. The potential effect of doxycycline on soil microbial activity was demonstrated by the nitrogen transformation test performed in compliance with the Organisation for Economic Co-operation and Development (OECD) Guideline No. 216. On day 28, the following nitrate concentrations of the control soil sample were found in the soil samples treated with different amounts of doxycycline: 76.9 %, 53.0 %, 65.6 %, 59.7 % and 77.1 %.
机译：由于多西环素相对于较老的四环素具有更高的生物利用度，因此已被不断增加用于食用动物的大量治疗。本文进行的研究是为了研究肥料改良土壤中四环素衍生物的降解率。在本实验中，堆肥后，将被强力霉素污染的肥料应用于农田，并进行了田间研究以研究强力霉素在土壤中的降解率。到20周的采样期结束时，在三种不同土壤深度下采集的土壤样品中，初始强力霉素的初始浓度分别约为20％，33％和18％。在0 cm，25 cm和50 cm的深度处，强力霉素在土壤中的半衰期计算值分别为66.5、76.3和59.4天。根据经济合作与发展组织（OECD）准则216号进行的氮转化试验证明了强力霉素对土壤微生物活性的潜在影响。在第28天，对照土壤样品中的以下硝酸盐浓度在用不同量的多西环素处理过的土壤样品中发现的含量分别为：76.9％，53.0％，65.6％，59.7％和77.1％。

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