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Relationship between air pollution and metal levels in cancerous and non-cancerous lung tissues

机译:癌性和非癌性肺组织中空气污染与金属含量之间的关系

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We aimed to check the relationships between levels of metals (Ca, Cd, Cu, Fe, Hg and Zn) in cancerous and non-cancerous lung tissues and their link to air pollution, expressed as particulate matter (PM) concentrations. The study also examines the influence on metal concentration in the lung tissue of patients' sex and the distance of their homes from the nearest emitter. We found that the general pattern of ascending concentrations in tumor tissue was as follows: Hg < Cd < Cu < Ca < Zn < Fe. In non-affected lung tissue the order of concentrations of Ca and Fe was reversed. With the exception of Cd and Cu, levels of metals were found in higher accumulations in non-cancerous tissue (e.g., Fe 326.423 and Ca 302.730g/g d.w) than in tumorous tissue (Fe 150.735 and Ca 15.025g/g d.w). Neither the PM10 (PM of a diameter of 10m) concentration nor sex revealed any connection with metal concentrations. The shorter the distance from the emitter, the higher the metal concentrations that tended to be observed for almost all metals, but a statistically significant (but weak) relationship was noted only for Cu in tumor tissue (r(s): -0.4869).
机译:我们旨在检查癌性和非癌性肺组织中金属(Ca,Cd,Cu,Fe,Hg和Zn)水平之间的关系以及它们与空气污染的关系,以颗粒物(PM)浓度表示。该研究还检查了患者性别对肺组织中金属浓度的影响以及离最近的放射源到他们家的距离。我们发现肿瘤组织中浓度升高的一般模式如下:Hg

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