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首页> 外文期刊>Journal of Environmental Science and Health. A, Toxic/Hazardous Substances & Environmental Engineering >Size-dependent toxicity of silica nano-particles to Chlorella kessleri
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Size-dependent toxicity of silica nano-particles to Chlorella kessleri

机译：二氧化硅纳米粒子对小球藻的大小依赖性毒性

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摘要

SiO_2 nano-particles were found to exhibit size-dependent toxicity toward the alga, Chlorella kessleri. Small SiO_2 nano-particles exhibit stronger toxicity: 50% inhibitory concentrations (IC_(50)) value for 5 nm = 0.8 ± 0.6%, 26 nm = 7.1 ± 2.8%, and 78 nm = 9.1 ± 4.7%. Enlargement of the cell body was observed by flow cytometry, which is due to the presence of structures that obstructed cell division. Optical and transmission microscopes were used to observe coagulated cells with incomplete division. Although the physiological effect of SiO_2 nano-particles was not clear, SiO_2 nano-particles are toxic, at least for algae in aquatic media. Under the transmission electron microscope, several amorphous structures appeared in the cells that were exposed to 5-nm silica nano-particles.
机译：SiO_2纳米颗粒被发现对藻类（小球藻）具有大小依赖性的毒性。较小的SiO_2纳米颗粒具有更强的毒性：5 nm的50％抑制浓度（IC_（50））值= 0.8±0.6％，26 nm = 7.1±2.8％和78 nm = 9.1±4.7％。通过流式细胞术观察到细胞体的增大，这是由于存在阻碍细胞分裂的结构。使用光学和透射显微镜观察不完整分裂的凝结细胞。尽管SiO_2纳米颗粒的生理作用尚不清楚，但SiO_2纳米颗粒至少对水生介质中的藻类有毒。在透射电子显微镜下，暴露于5-nm二氧化硅纳米粒子的细胞中出现了几种无定形结构。

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