...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of Experimental Botany >HDA6 is required for jasmonate response, senescence and flowering in Arabidopsis
【24h】

HDA6 is required for jasmonate response, senescence and flowering in Arabidopsis

机译：拟南芥茉莉酸响应，衰老和开花需要HDA6

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Post-translational modifications of histones, including acetylation, play a key role in modulating dynamic changes in chromatin structure and gene activity. Histone acetylation is modulated through the action of histone acetyltransferases and deacetylases. HDA6 is a RPD3-type histone deacetylase in Arabidopsis. The Arabidopsis HDA6 mutant, axe1-5, and HDA6 RNA-interfering (HDA6-RNAi) plants displayed higher levels of acetylated H3 compared with wild-type, suggesting that HDA6 affects histone acetylation levels globally. The expression of the jasmonate responsive genes, PDF1.2, VSP2, JIN1, and ERF1, was down-regulated in axe1-5 and HDA6-RNAi plants. Furthermore, axe1-5 and HDA6-RNAi plants displayed increased leaf longevity compared with the wild type. The expression of the senescence-associated genes, SAG12 and SEN4, was down-regulated in the axe1-5 and HDA6-RNAi plants. In addition, axe1-5 and HDA6-RNAi plants displayed late-flowering. The expression of FLC was up-regulated and hyperacetylated in axe1-5 and HDA6-RNAi plants, suggesting that HDA6 is required to deacetylate FLC chromatin and thereby repress its expression. Our results suggest that HDA6 is involved in jasmonate response, senescence, and flowering in Arabidopsis.
机译：组蛋白的翻译后修饰（包括乙酰化）在调节染色质结构和基因活性的动态变化中起关键作用。组蛋白乙酰化是通过组蛋白乙酰转移酶和脱乙酰酶的作用来调节的。 HDA6是拟南芥中的RPD3型组蛋白脱乙酰基酶。与野生型相比，拟南芥HDA6突变体，axe1-5和HDA6 RNA干扰（HDA6-RNAi）植物显示出更高水平的乙酰化H3，这表明HDA6会影响全球组蛋白的乙酰化水平。茉莉酸应答基因PDF1.2，VSP2，JIN1和ERF1的表达在axe1-5和HDA6-RNAi植物中被下调。此外，与野生型相比，axe1-5和HDA6-RNAi植物显示出更长的叶片寿命。衰老相关基因SAG12和SEN4的表达在axe1-5和HDA6-RNAi植物中被下调。此外，axe1-5和HDA6-RNAi植物显示出晚花期。在axe1-5和HDA6-RNAi植物中，FLC的表达上调并被高度乙酰化，这表明需要HDA6才能使FLC染色质脱乙酰化，从而抑制其表达。我们的结果表明，HDA6与拟南芥中的茉莉酸酯响应，衰老和开花有关。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号