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首页> 外文期刊>Journal of Food Science >Green Tea Formulations with Vitamin C and Xylitol on Enhanced Intestinal Transport of Green Tea Catechins
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Green Tea Formulations with Vitamin C and Xylitol on Enhanced Intestinal Transport of Green Tea Catechins

机译：含维生素C和木糖醇的绿茶配方可增强绿茶儿茶素的肠道运输

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摘要

The effect of green tea formulated with vitamin C and xylitol on intestinal cell transport of gallated and nongallated catechin was studied. The transport of catechins from both apical to basolateral and basolateral to apical directions was measured. The effect of vitamin C (4, 10, 20 ppm), xylitol (11, 27.5, 55 ppm), and combinations of both on the intestinal transport rate of catechins was examined. The efflux value (Pb→a/Pa→b) of (-)-epigallocatechin (EGC), (-)-epigallocatechin gallate (EGCG), (-)-epicatechin (EC), and (-)-epicatechin gallate (ECG) was 0.26, 0.22, 1.22, and 0.17, respectively, indicating that EC appeared to be less absorbed compared with other catechins. The addition of xylitol (11, 27.5, 55 ppm) and vitamin C (4, 10, 20 ppm) and in combination enhanced transport rate of nongallated catechins such as EC and EGC. For EC, vitamin C was revealed to be the most effective on intestinal transport, implying the inhibition of the efflux transport mechanism of EC. Intestinal transport of gallated catechins significantly increased from catechins formulated with vitamin C and xylitol in a dose-dependent manner compared to the catechin-only formulation. Results provide a potential strategy to enhance the delivery and bioavailability of catechins in humans by modulating green tea formulation with vitamin C and xylitol.
机译：研究了由维生素C和木糖醇配制的绿茶对没食子儿茶素和没食子儿茶素的肠道细胞运输的影响。测量儿茶素从顶端到基底外侧以及从基底外侧到顶端方向的转运。研究了维生素C（4、10、20 ppm），木糖醇（11、27.5、55 ppm）以及两者的组合对儿茶素肠转运速率的影响。 （-）-表没食子儿茶素（EGC），（-）-表没食子儿茶素没食子酸酯（EGCG），（-）-表儿茶素（EC）和（-）-表儿茶素没食子酸酯（ECG）的流出值（Pb→a / Pa→b） ）分别为0.26、0.22、1.22和0.17，表明EC与其他儿茶素相比似乎吸收较少。木糖醇（11、27.5、55 ppm）和维生素C（4、10、20 ppm）的添加以及结合在一起可提高未加盖儿基儿茶素（如EC和EGC）的转运速率。对于EC，维生素C被证明对肠运输最有效，这意味着EC的外排运输机制受到抑制。与仅使用儿茶素的制剂相比，用维生素C和木糖醇配制的儿茶素的没食子酸儿茶素的肠道运输量显着增加。结果提供了一种潜在的策略，可通过用维生素C和木糖醇调节绿茶配方来增强儿茶素在人体内的递送和生物利用度。

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  • 来源
    《Journal of Food Science》 |2013年第6期|685-690|共6页
  • 作者

    Jae-Hwan Chung; Sol Kim; Sang-Jun Lee; Jin-Oh Chung; Yu-Jin Oh; Soon-Mi Shim;

  • 作者单位

    Dept. of Food Science & Technology and Carbohydrate Bioproduct Research Center, Sejong Univ., 98 Gunja-dong, Gwangjin-gu, Seoul, 143-747,Republic of Korea;

    Div. of Food Policy, 75 Yulgong-ro, Jongno-gu, Seoul, 110-793, Republic of Korea;

    Health Science Research Inst., AmorePacificR&D Center, Yongin-si, Gyeonggi-do, 446-729, Rcipublic of Korea;

    Health Science Research Inst., AmorePacificR&D Center, Yongin-si, Gyeonggi-do, 446-729, Rcipublic of Korea;

    Health Science Research Inst., AmorePacificR&D Center, Yongin-si, Gyeonggi-do, 446-729, Rcipublic of Korea;

    Dept. of Food Science & Technology and Carbohydrate Bioproduct Research Center, Sejong Univ., 98 Gunja-dong, Gwangjin-gu, Seoul, 143-747,Republic of Korea;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    catechin; intestinal transport; vitamin C; xylitol;

    机译：儿茶素肠运输;维生素C;木糖醇;

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