Reduction of Hepatitis A Virus on FRhK-4 Cells Treated with Korean Red Ginseng Extract and Ginsenosides

Min Hwa Lee; Bog-Hieu Lee; Sanghyun Lee; Changsun Choi

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Reduction of Hepatitis A Virus on FRhK-4 Cells Treated with Korean Red Ginseng Extract and Ginsenosides

机译：用红参提取物和人参皂甙处理的FRhK-4细胞减低甲型肝炎病毒

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摘要

Red ginseng has a variety of bioactive functions and is widely used as an oriental medicinal herb and food ingredient. The aim of this study was to investigate the antiviral effect of red ginseng extract and ginsenosides against hepatitis A virus (HAV). To examine the antiviral effect against HAV, 0 to 10 μg/mL of red ginseng and purified ginsenoside Rbl and Rg1 were pre-treated or co-treated on FRhK-4 cells: The HAV titer decreased significantly in all groups pretreated with red ginseng or purified ginsenosides. The reduction of HAV was significant in FRhK-4 cells pre-treated only with red ginseng. Our results showed that red ginseng and ginsenoside Rgl and Rb1 could decrease HAV titers.

机译：红参具有多种生物活性功能，被广泛用作东方草药和食品成分。这项研究的目的是研究红参提取物和人参皂苷对甲型肝炎病毒（HAV）的抗病毒作用。为了检查抗HAV的抗病毒作用，在FRhK-4细胞上预处理或共同处理了0至10μg/ mL的红参和纯化的人参皂苷Rbl和Rg1：在用红参或RP预处理的所有组中，HAV滴度均显着降低。纯化的人参皂甙。在仅用红参预处理的FRhK-4细胞中，HAV的降低是显着的。我们的结果表明，红参和人参皂苷Rgl和Rb1可以降低HAV效价。

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来源
《Journal of Food Science》 |2013年第9期|1412-1415|共4页
作者
Min Hwa Lee; Bog-Hieu Lee; Sanghyun Lee; Changsun Choi;
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作者单位

Dept. of Integrative Plant Science, Chung-Ang Univ., Ansung, 456-756, Republic of Korea, Chung-Ang Univ., Ansung, 456-156, Republic of Korea;

Dept. of Integrative Plant Science, Chung-Ang Univ., Ansung, 456-756, Republic of Korea, Chung-Ang Univ., Ansung, 456-156, Republic of Korea;

Dept. of Integrative Plant Science, Chung-Ang Univ., Ansung, 456-756, Republic of Korea, Chung-Ang Univ., Ansung, 456-156, Republic of Korea;

Dept. of Integrative Plant Science, Chung-Ang Univ., Ansung, 456-756, Republic of Korea, Chung-Ang Univ., Ansung, 456-156, Republic of Korea;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);
原文格式 PDF
正文语种 eng
中图分类
关键词
antiviral; hepatitis A virus; ginsenoside Rb1; ginsenoside Rg1; red ginseng;

机译：抗病毒物质;甲型肝炎病毒;人参皂甙Rb1;人参皂苷Rg1;红参;

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专利

1. Antiviral Effect of Korean Red Ginseng Extract and Ginsenosides on Murine Norovirus and Feline Calicivirus as Surrogates for Human Norovirus [J] . Min Hwa Lee, Bog-Hieu Lee, Ji-Youn Jung, Journal of Ginseng Research . 2011,第4期

机译：红参提取物和人参皂甙对小鼠诺如病毒和猫杯状病毒作为人类诺如病毒的替代物的抗病毒作用。
2. Expression of antiviral cytokines in Crandell-Reese feline kidney cells pretreated with Korean red ginseng extract or ginsenosides [J] . Lee Min Hwa, Seo Dong Joo, Kang Ju-Hee, Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research . 2014,第Null期

机译：红参提取物或人参皂甙预处理后的克兰德尔·里斯猫肾细胞中抗病毒细胞因子的表达
3. Enzymatic transformation of ginsenosides in Korean Red Ginseng (Panax ginseng Meyer) extract prepared by Spezyme and Optidex [J] . Hyeon-Son Choi, Sun Young Kim, Yooheon Park, Journal of Ginseng Research . 2014,第4期

机译：Spezyme和Optidex制备的韩国红参提取物中的人参皂苷的酶促转化
4. Identification of ginsenosides Rc, Rb2, Rb3 and related malonyl-ginsenosides in panax ginseng extracts by using RRLC-Q-TOF-MS/MS [C] . Jinghui Sun, Jun Mi, Qiujie Qin, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：用RRLC-Q-TOF-MS / MS鉴定人参提取物中的人参皂苷Rc，Rb 2 ，Rb 3 及相关的丙二酰人参皂苷
5. The effect of root parts of Korean Red ginseng (Panax ginseng C.A. Meyer) and alcohol extracts of American ginseng (Panax quinquefolius L.) and Korean Red ginseng on glycemic parameters. [D] . De Souza, Leanne R. 2008

机译：高丽红参（Panax ginseng C.A. Meyer）的根部以及西洋参（Panax quinquefolius L.）和高丽红参的酒精提取物对血糖参数的影响。
6. Antiviral Effect of Korean Red Ginseng Extract and Ginsenosides on Murine Norovirus and Feline Calicivirus as Surrogates for Human Norovirus [O] . Min Hwa Lee, Bog-Hieu Lee, Ji-Youn Jung, 2011

机译：韩国红参提取物和人参皂甙对小鼠诺如病毒和猫杯状病毒作为人类诺如病毒的替代物的抗病毒作用。
7. Enzymatic transformation of ginsenosides in Korean Red Ginseng (Panax ginseng Meyer) extract prepared by Spezyme and Optidex [O] . Hyeon-Son Choi, Sun Young Kim, Yooheon Park, 2014

机译：spezyme和Optidex制备的韩国红参（panax ginseng meyer）提取物中人参皂苷的酶促转化

Reduction of Hepatitis A Virus on FRhK-4 Cells Treated with Korean Red Ginseng Extract and Ginsenosides

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