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An alternative method to assess permeation through disposable gloves

机译：一种通过一次性手套评估渗透的替代方法

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摘要

Previously, we have demonstrated the capability of activated charcoal cloth (ACC) to assess dermal exposure to VOCs. Here we investigated whether ACC patches can be used as an under-glove indicator to evaluate the ingress of toluene through disposable gloves in a controlled environment, and compared these results to the amount of toluene ingress determined from the standardized test methods for determining chemical permeation through PPE. In a test chamber, with plugs for air sampling, five to six ACC patches were placed on a mannequin hand underneath disposable gloves (latex, nitrile, neoprene, polymer laminate). Three work-exposure scenarios were simulated to assess toluene ingress through the different gloves: vapor exposure; spray exposure, and immersion. The standard permeation test, using a diffusion cell, was carried with glove material of the palm, with continuous contact conditions. In all of ACC test, the order of toluene ingress was latex neoprene nitrile Barrier, but for the standardized testing, the order of the neoprene and nitrile was reversed, and nitrile had higher levels of toluene ingress. These results show the need to think beyond standard testing techniques for occupational exposure to hazardous substances, and the added value of ?application style? testing.
机译：以前，我们已经证明了活性炭布（ACC）的能力，以评估DOC的皮肤暴露。在这里，我们研究了ACC贴片是否可以用作甲基药物，以通过受控环境中的一次性手套评估甲苯的进入，并将这些结果与由标准化试验方法确定的甲苯进入的量进行比较，以确定化学渗透的标准化试验方法PPE。在一个测试室中，用空气采样插头，将五到六个ACC贴片放在一次性手套（乳胶，丁腈，氯丁橡胶，聚合物层压板）下的时装模特上。模拟三种工作场景，以评估甲苯进入通过不同的手套：蒸气暴露;喷雾暴露，浸泡。使用扩散细胞的标准渗透测试用手套材料进行，具有连续接触条件。在所有ACC测试中，甲苯进入的顺序是乳胶＆氯丁橡胶＆丁腈＆屏障，但对于标准化测试，氯丁橡胶和腈的顺序颠倒，丁腈具有较高水平的甲苯进入。这些结果表明，需要思考职业暴露于危险物质的标准测试技术，以及附加值的施用式？测试。

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  • 来源
    《Journal of Hazardous Materials》 |2021年第5期|125045.1-125045.10|共10页
  • 作者

    Creta Matteo; Savory Luke D.; Duca Radu-Corneliu; Chu Wai Kei; Poels Katrien; Pan Jin; Zheng Jiamin; Godderis Lode; Draper Mike; Vanoirbeek Jeroen A. J.;

  • 作者单位

    Univ Leuven KU Leuven Environm & Hlth Leuven Belgium;

    Willerby Ansell UK Ltd Kingston Upon Hull N Humberside England;

    Univ Leuven KU Leuven Environm & Hlth Leuven Belgium|Natl Hlth Lab LNS Unit Environm Hyg & Human Biol Monitoring Dept Hlth Protect Luxembourg Luxembourg;

    Univ Leuven KU Leuven Environm & Hlth Leuven Belgium;

    Univ Leuven KU Leuven Environm & Hlth Leuven Belgium;

    Ansell Xiamen Ltd 39 East 2nd Haijing Rd Xiamen 361026 Peoples R China;

    Ansell Xiamen Ltd 39 East 2nd Haijing Rd Xiamen 361026 Peoples R China;

    Univ Leuven KU Leuven Environm & Hlth Leuven Belgium|Idewe External Serv Prevent & Protect Work Heverlee Belgium;

    Willerby Ansell UK Ltd Kingston Upon Hull N Humberside England;

    Univ Leuven KU Leuven Environm & Hlth Leuven Belgium;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Toluene; Activated charcoal patch; Organic vapor monitor; Gloves; Personal protective equipment (PPE); Permeation;

    机译：甲苯;活性炭贴片;有机蒸气监测器;手套;个人防护装备（PPE）;渗透;

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