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On estimators of medical costs with censored data

机译:用审查数据估算医疗费用

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In the assessment of cost-effectiveness of alternative medical technologies, it is necessary to estimate the mean total cost per patient over the relevant patient population. Where information about costs comes from a clinical trial with censored data, care is needed to estimate mean total costs. We examine the theoretical connections between the two most widely used of a growing range of nonparametric estimators of costs under censoring. By clarifying the relationships between these simple methods we hope to make them more accessible and to facilitate the take-up of more sophisticated techniques. Recommendations are offered regarding the most appropriate of the available methods, but also on the potential for greater efficiency through parametric modelling.
机译:在评估替代医疗技术的成本效益时,有必要估算相关患者群体中每位患者的平均总费用。如果有关费用的信息来自带有审查数据的临床试验,则需要谨慎估计平均总费用。我们研究了在审查制度下成本越来越高的非参数估计器中使用最广泛的两种方法之间的理论联系。通过阐明这些简单方法之间的关系,我们希望使它们更易于访问,并促进采用更复杂的技术。提供有关最合适的可用方法的建议,但也建议通过参数建模提高效率的潜力。

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