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首页> 外文期刊>Journal of Huazhong University of Science and Technology >Effects of Minimally Invasive Puncture and Drainage of Intracranial Hematoma on the Blood-brain Barrier in Patients with Cerebral Hemorrhage
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Effects of Minimally Invasive Puncture and Drainage of Intracranial Hematoma on the Blood-brain Barrier in Patients with Cerebral Hemorrhage

机译：微创穿刺引流颅内血肿对脑出血患者血脑屏障的影响

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摘要

The effects of minimally invasive surgery on the blood-brain barrier (BBB) of 30 patients with cerebral hemorrhage were investigated. Difference of the BBB index and serum MBP concentration were assessed in 15 cases of conservative treatment group and 15 cases of minimally invasive surgery group. The BBB index in minimally invasive surgery group was significantly lower than in conservative treatment group (P < 0.05), and the BBB index in the two treatment groups was significantly higher than in control group (P < 0.01). Serum MBP concentration in minimally invasive surgery group was significantly lower than in conservative treatment group (P < 0.05), and that in the two treatment groups was significantly higher than in control group (P < 0.01). It was suggested the permeability of BBB in patients with cerebral hemorrhage was increased, and BBB index and serum MBP concentration in patients with cerebral hemorrhage were increased. Minimally invasive surgery can reduce the lesion of cytotoxicity to BBB and cerebral edema.
机译：研究了微创手术对30例脑出血患者的血脑屏障（BBB）的影响。在15例保守治疗组和15例微创手术组中评估BBB指数和血清MBP浓度的差异。微创手术组的BBB指数显着低于保守治疗组（P <0.05），两个治疗组的BBB指数显着高于对照组（P <0.01）。微创手术组的血清MBP浓度显着低于保守治疗组（P <0.05），两个治疗组的血清MBP浓度显着高于对照组（P <0.01）。提示脑出血患者血脑屏障通透性增加，脑出血患者血脑屏障指数和血清MBP浓度升高。微创手术可以减少对BBB的细胞毒性损害和脑水肿。

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