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首页> 外文期刊>Journal of Laser Applications >Low-energy helium-neon laser ensures knee cartilage repair: An experimental short-term assay in rabbits
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Low-energy helium-neon laser ensures knee cartilage repair: An experimental short-term assay in rabbits

机译：低能氦氖激光确保膝关节软骨修复：兔实验性短期测定

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Objectives. The purpose of this study was to evaluate the influence of low-power helium-neon laser on cartilage damage using an experimental short-term assay in rabbits. Material and Methods. A total of 21 adult male New Zealand rabbits underwent bilateral knee cartilage damage using a spherical bur. Helium-neon laser light with power of 6 J/cm~2 and wavelength of 632.8 nm was applied on the left knees submitted to surgical procedures only. The right knees lesions served as negative control (nonexposed to laser therapy). All animals were randomized and seven animals were killed at postoperative days 7, 21, and 40 days. Results. At seven days, similar histopathological patterns were noted for laser exposed and nonexposed knees. At 21 days, the control group showed an organized fibrous tissue inside the lesion, whereas knees exposed to laser therapy pointed out a cartilage tissue filling the lesion in the majority of treated knees. At 40 days, a well-organized fibrous tissue filled fully the lesion in the control group. On the other hand, the laser exposed knees showed a hyaline cartilage filled the lesion completely. Conclusions. Taken together, these results indicate that a low-energy laser is able to induce cartilage neoformation after 40 days following therapy.
机译：目标。这项研究的目的是使用兔实验性短期试验评估低功率氦氖激光对软骨损伤的影响。材料与方法。总共21只成年雄性新西兰兔使用球形钻对双侧膝关节软骨进行了损伤。功率为6 J / cm〜2且波长为632.8 nm的氦氖激光仅应用于左膝进行手术。右膝盖病变用作阴性对照（未接受激光治疗）。将所有动物随机化，并在术后第7、21和40天处死7只动物。结果。在第7天，对于激光暴露和未暴露的膝盖，发现了相似的组织病理学模式。对照组在第21天显示病变内部有组织的纤维组织，而接受激光治疗的膝盖指出，在大多数接受治疗的膝盖中，软骨组织填充了病变。在第40天，在对照组中，组织良好的纤维组织完全充满了病变。另一方面，激光暴露的膝盖显示出透明的软骨完全充满了病变。结论。综上所述，这些结果表明，低能量激光能够在治疗后40天后诱发软骨新形成。

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