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首页> 外文期刊>Journal of Laser Applications >Three-dimensional biomimetic microchannel network by laser direct writing
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Three-dimensional biomimetic microchannel network by laser direct writing

机译：激光直写三维仿生微通道网络

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摘要

Application of laser direct writing to the fabrication of microchannel networks for tissue engineering was presented. A Q-switched Nd:YAG laser with fundamental wavelength was used. Multidepth, multiwidth microstructures on silicon were machined without photolithography-based methods. The molten material inside the microchannel was ejected with a modified assist gas, and thus the volume of laser ablation was increased. The debris build-up due to the strong thermal reaction of silicon to the nanosecond IR laser pulse was cleaned up with chemical wet etching in a mixture of hydrofluoric acid (HF) and nitric acid (HNO3). The chemical etching of the laser ablated silicon surface was studied to measure the etching rate and to observe the evolution of the surface morphology. Using the laser machined silicon structures as a mold, a poly(dimethylsiloxane) (PDMS) replica was created. Flow visualization was carried out with the patterned PDMS.
机译：介绍了激光直接写入在组织工程微通道网络制造中的应用。使用具有基本波长的Q开关Nd：YAG激光器。无需基于光刻的方法即可加工硅上的多深度，多宽度的微结构。微通道内部的熔融材料被喷射有改良的辅助气体，因此增加了激光烧蚀的体积。在氢氟酸（HF）和硝酸（HNO3）的混合物中，通过化学湿法蚀刻清除了由于硅与纳秒级IR激光脉冲的强烈热反应而产生的碎屑堆积。研究了激光烧蚀硅表面的化学刻蚀，以测量刻蚀速率并观察表面形貌的演变。使用激光加工的硅结构作为模具，创建了聚二甲基硅氧烷（PDMS）复制品。用图案化的PDMS进行流动可视化。

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