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首页> 外文期刊>Journal of Materials Research >Potency of a novel synthesized Ag-eugenol nanoemulsion for treating some bacterial and fungal pathogens
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Potency of a novel synthesized Ag-eugenol nanoemulsion for treating some bacterial and fungal pathogens

机译：一种新型合成的Ag-eUgenol纳米乳液治疗一些细菌和真菌病原体的效力

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摘要

The current research deals with the synthesis and validation of the novel Ag-eugenol nanoemulsion (O/W).The synthesized Ag-eugenol nanoemulsion was validated by DLS,TEM, FT-IR, UV-VIS spectral analysis; TEM reveals the particles an average size of 30 nm and SEM images confirm spherical morphology of particles.Zeta potential measurements, presented a negative average zeta potential of-25 mV.EDX analysis showed typical absorption peaks at 0.25 keV and 3 keV that confirm the presence of AgNPs.Elemental mapping of Ag-eugenol nanoemulsion confirms the presence of silver, eugenol moiety and the AgNPs are nucleated by eugenol moiety.Eugenol, eugenol nanoemulsion (5 μg/ ml), AgNPs (25 ppm) and Ag-eugenol nanoemulsion (12.5 ppm AgNPs∶ eugenol 2.5 μg/ml) solutions were tested for their antimicrobial potency against Staphylococcus aureus, Bacillus subtilis, Escherichia coli, and Proteus vulgaris.Ag-eugenol nanoemulsion was effective against both tested fungi; A fumigatus and C.albicans with MIC 12.5∶2.5 ppm∶μg/ml and 6.25∶1.25 ppm∶μg/ml, respectively, comparing to a negative effect of eugenol nanoemulsion.
机译：目前的研究涉及新型Ag-eugenol纳米乳液（O / W）的合成和验证。通过DLS，TEM，FT-IR，UV-Vis光谱分析验证了合成的Ag-eUgenol纳米乳液; TEM揭示粒子平均大小为30nm和sem图像的粒子粒子形态的粒子形态。zeta电位测量的粒子形貌，呈现了-25 mv.edx分析的负平均Zeta电位，显示出0.25keV和3kev的典型吸收峰，确认存在agnps.Agnps.Ag-eugenol纳米乳液的位置映射证实银，丁香酚部分和酰胺的存在由丁烯醇部分核解丁烯酚，丁烯醇纳米乳剂（5μg/ ml），AgNPS（25ppm）和Ag-eUgenol纳米乳液（12.5测试PPM AgNPS：Eugenol2.5μg/ ml）溶液对金黄色葡萄球菌，枯草芽孢杆菌，大肠杆菌和Protgaris.Ag-eugenol纳米乳剂进行抗菌药物抗菌效力。与麦克风12.5:2.5 ppm：μg/ ml和6.25：1.25ppm:mg / ml的Fumigatus和C.albicans分别比较丁烯醇纳米乳液的负面影响。

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  • 来源
    《Journal of Materials Research》 |2021年第7期|1524-1537|共14页
  • 作者

    Farag M.Mosallam; Eman A.Helmy; Mahmoud M.Bendary; Ahmed I.El-Bata;

  • 作者单位

    Drug Microbiology Laboratory Drug Radiation Research Department National Center for Radiation Research and Technology (NCRRT) Egyptian Atomic Energy Authority Cairo Egypt;

    Regional Center for Mycology and Biotechnology (RCMB) Al-Azhar University Cairo Egypt;

    Microbiology and Immunology Department Faculty of Pharmacy Port Said University Port Said Egypt;

    Drug Microbiology Laboratory Drug Radiation Research Department National Center for Radiation Research and Technology (NCRRT) Egyptian Atomic Energy Authority Cairo Egypt;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
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  • 正文语种 eng
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